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NAMZARIC

NAMZARIC

Used for Dementia

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Manufactured by Forest Pharmaceuticals

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

NAMZARIC Uses, Side Effects, Interactions, Warnings & Dosing

What is NAMZARIC?

What is NAMZARIC?

NAMZARIC is the brand name for memantine hydrochloride extended-release and donepezil in an oral capsule.

What dosages is NAMZARIC available in?

What dosages is NAMZARIC available in?

NAMZARIC is available as an oral capsule that contains one of the following:

  • 14 mg memantine hydrochloride extended-release and 10 mg donepezil hydrochloride
  • 28 mg memantine hydrochloride extended-release and 10 mg donepezil hydrochloride
What is NAMZARIC used for?

What is NAMZARIC used for?

NAMZARIC is a NMDA antagonist / Acetylcholinesterase inhibitor and is used to treat moderate-to-severe dementia in people with Alzheimer’s disease (AD).

How does NAMZARIC work?

How does NAMZARIC work?

NAMZARIC is a combination of two medications that treats moderate-to-severe dementia in people with Alzheimer’s disease. Memantine (an NMDA antagonist) lowers the activity of certain proteins in your brain. Donepezil (an acetylcholinesterase inhibitor) raises the levels of acetylcholine in the brain. These two medications work together to lower the symptoms of Alzheimer’s.

How do I take NAMZARIC?

How do I take NAMZARIC?

NAMZARIC is dosed as follows:

  • If your condition is stable on donepezil only: The typical starting dose is 7 mg/10 mg (memantine/donepezil) by mouth once per day in the evening. Your dose will be slowly raised in 7 mg increments until you reach 28 mg/10 mg (memantine/donepezil) once per day
  • If your condition is stable on both donepezil and memantine (separately): The typical starting dose is 28 mg/10 mg (memantine/donepezil) by mouth once per day in the evening

Your dose may differ if you have kidney problems.

Is it safe for me to take NAMZARIC?

Is it safe for me to take NAMZARIC?

NAMZARIC is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. NAMZARIC is contraindicated in patients with known hypersensitivity to
memantine hydrochloride, donepezil hydrochloride, piperidine derivatives, or to any excipients used in the formulation.

NAMZARIC Common Side Effects

NAMZARIC Common Side Effects

Common side effects of NAMZARIC:

  • Headache
  • Diarrhea
  • Nausea
  • Vomiting
  • Dizziness
  • Loss of appetite (anorexia)
  • Bruising
NAMZARIC Serious Side Effects

NAMZARIC Serious Side Effects

Serious side effects are rare with NAMZARIC. Contact your healthcare provider immediately if you experience any of the following.

  • Chest pain
  • Seizure
  • Slow heartbeat: fainting
  • Stomach ulcers and bleeding: worsening upset stomach, heartburn, indigestion
Effects of other drugs, drug classes and over-the-counter products on NAMZARIC

Effects of other drugs, drug classes and over-the-counter products on NAMZARIC

The following medications may interact with NAMZARIC:

  • Combined use with NMDA antagonists: use with caution.
  • NAMZARIC may interfere with anticholinergic medications
  • Concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists may lead to synergistic effect
Who makes NAMZARIC?

Who makes NAMZARIC?

Forest Pharmaceuticals

Is NAMZARIC safe in pregnancy?

Is NAMZARIC safe in pregnancy?

It is not known if NAMZARIC can harm an unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

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What to do if you missed your NAMZARIC dose

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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