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Mirena is the brand name for a levonorgestrel-releasing intrauterine system.

Mirena is available as a sterile intrauterine system consisting of a T-shaped polyethylene frame with a steroid reservoir containing 52 mg levonorgestrel packaged within a sterile inserter.

Mirena is a progestin and is used for the following:

• Prevent pregnancy for up to 8 years
• Relieve heavy menstrual periods for up to 5 years

Mirena is a small device placed in the uterus that slowly releases a progestin hormone called levonorgestrel. This hormone prevents pregnancy by stopping your ovaries from releasing an egg. Levonorgestrel also makes it difficult for sperm to enter the uterus and for a fertilized egg to implant in the uterus. Mirena works to treat heavy periods by thinning the lining of your uterus.

Mirena is dosed as follows:

• Your provider will place Mirena inside the uterus at their office
• Prevent pregnancy: Mirena IUD (levonorgestrel) will stay in place for up to 8 years. Then, your provider will remove the IUD at their office
• Heavy menstrual bleeding: Mirena IUD (levonorgestrel) will stay in place for up to 5 years. Then, your provider will remove the IUD at their office

Mirena is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following apply.
Pregnancy or suspicion of pregnancy. Cannot be used for post-coital contraception (emergency contraception).
Congenital or acquired uterine anomaly if it distorts the uterine cavity. Acute pelvic inflammatory disease (PID) or a history of PID unless there has been a subsequent intrauterine pregnancy.

• Postpartum endometritis or infected abortion in the past 3 months
• Known or suspected uterine or cervical malignancy
• Known or suspected breast cancer or other progestin-sensitive cancer
• Uterine bleeding of unknown etiology
• Untreated acute cervicitis or vaginitis or other lower genital tract infections
• Acute liver disease or liver tumor (benign or malignant).
• Increased susceptibility to pelvic infection
• A previous intrauterine device (IUD) that has not been removed
• Hypersensitivity to any component of Mirena

Common side effects of Mirena:

• Abnormal uterine bleeding
• Stomach or pelvic pain
• No menstrual bleeding
• Headaches or migraines
• More vaginal discharge than usual
• Vaginal irritation

Serious side effects are rare with Mirena. Contact your healthcare provider immediately if you experience any of the following.

• Ectopic pregnancy: severe, unexplainable pelvic pain along with unusual vaginal bleeding
• Severe infection: fever, chills, confusion, fatigue

• No drug-drug interaction studies have been conducted with Mirena. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Bayer Healthcare

Mirena is not indicated during pregnancy. If pregnancy occurs during treatment let your healthcare provider know immediately.

• Levonorgestrel-Releasing Intrauterine System