MICROZIDE

This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide belongs to a class of drugs known as diuretics or ‘water pills.’ It works by increasing urine production.

Hydrochlorothiazide is used alone or in combination with other medications to manage high blood pressure (hypertension). Prolonged high blood pressure can strain the heart and arteries, potentially affecting their normal function.

Microzide may interact with various medications that can induce dizziness, such as cold medicines, pain relievers, muscle relaxants, drugs for seizures, depression or anxiety, as well as lithium, digoxin, cholestyramine, colestipol, steroids, other blood pressure medications, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Hydrochlorothiazide is utilized to treat high blood pressure and cases of edema (fluid retention in the body). This medication belongs to the diuretic class, working by prompting the kidneys to eliminate excess water and salt.

Hydrochlorothiazide (Microzide) side effects include changes in electrolyte levels, dizziness, weakness, headaches, elevated blood glucose, sexual problems, and, in severe cases, pancreatitis.

To prevent dehydration, it is advisable to consume ample fluids unless otherwise instructed by your doctor. If you have diabetes, hydrochlorothiazide can impact your blood sugar levels. Regularly monitor your blood sugar as per your doctor’s guidance.

Hydrochlorothiazide is contraindicated in patients with kidney diseases due to its potential stress on the kidneys. It should be avoided by individuals with a history of liver diseases, diabetes, low blood potassium, and reduced blood sodium levels.

Yes, hydrochlorothiazide is a diuretic, commonly known as a ‘water pill,’ that increases urine production to help the body eliminate excess fluid. It is advisable to avoid taking hydrochlorothiazide just before bedtime to minimize nighttime urination.

For optimal results, take this medication on an empty stomach. Adhere closely to your doctor’s dietary recommendations, which may include incorporating potassium-rich foods like oranges or bananas to prevent potassium loss.

Individuals with heart failure, who often experience weight gain due to fluid retention (edema), are frequently prescribed diuretic medications. As expected, frequent urination is one of the most common side effects of water pills.

The exact mechanism of action of hydrochlorothiazide is not fully understood, but it is believed to reduce excess salt and water in the body. This eases the workload on the heart, lowering blood pressure and reducing swelling.

Common side effects of hydrochlorothiazide may include nausea, muscle weakness, extreme dry mouth and thirst, dizziness, and physical weakness.

Examples of other classes of antihypertensive medications include ACE inhibitors (e.g., benazepril, zofenopril, lisinopril), angiotensin II receptor blockers (e.g., losartan, valsartan), beta-blockers (e.g., acebutolol, atenolol, bisoprolol), and calcium channel blockers (e.g., amlodipine, diltiazem).

Inform your doctor about your kidney disease, as hydrochlorothiazide may not be suitable for you. Disclose any history of diabetes, asthma, gout, systemic lupus erythematosus (SLE), high cholesterol, or kidney and liver diseases.

When taking diuretics like furosemide, avoid excessive salt in your diet, as this can diminish their effectiveness. Refrain from consuming highly salted foods such as processed meals and consider not adding extra salt while cooking or at the table.

MICROZIDE 500 TABLET is prescribed for treating mild to moderate susceptible bacterial and other microorganism infections, including chest, throat, and nasal infections such as bronchitis, pneumonia, tonsillitis, sore throat, and sinusitis.

To prevent dehydration, ensure adequate fluid intake, unless otherwise instructed by your doctor. If you have diabetes, be aware that hydrochlorothiazide may affect your blood sugar levels. Monitor your blood sugar regularly under your doctor’s guidance, and adjustments to your diabetes treatment plan may be necessary.

MICROZIDE is indicated for the management of hypertension, either as the sole therapeutic agent or in combination with other antihypertensive medications.

Do not use Microzide (hydrochlorothiazide) if you are allergic to it, sulfa drugs, unable to urinate, taking dofetilide, or lithium.

Hydrochlorothiazide can be used to treat calcium-containing kidney stones by reducing the excretion of calcium in urine, thereby decreasing the formation of stones.

If you notice new skin changes or growths while taking hydrochlorothiazide, consult your doctor. Dizziness, lightheadedness, and fainting upon quick transitions from a lying position are potential side effects, particularly when initiating hydrochlorothiazide use.

Hydrochlorothiazide begins to take effect within 2 hours of administration, with its peak effectiveness occurring around 4 hours after intake. The diuretic and blood pressure-lowering effects of hydrochlorothiazide can persist for six to 12 hours.

For adults, the typical dosage ranges from 25 to 100 milligrams (mg) daily, either as a single dose or divided into smaller doses. Some individuals may be instructed by their doctor to take this dosage every other day or on 3 to 5 days per week. Children’s doses are determined based on body weight and must be prescribed by a healthcare professional.

If you are prescribed a once-daily dose, it’s recommended to take it in the morning after breakfast. If multiple doses are prescribed per day, the final dose should not be taken later than 6 p.m., unless otherwise directed by your healthcare provider.

Typically, it takes about two to four days for the effects of hydrochlorothiazide to become noticeable. This may manifest as reduced fluid retention and lower blood pressure readings. If no improvement is observed within this timeframe, your doctor may adjust your dose or consider alternative treatment options.

Yes, hydrochlorothiazide is classified as a diuretic or ‘water pill’ that promotes increased urine production, aiding the body in eliminating excess fluid. To avoid nighttime urination, it’s advisable not to take hydrochlorothiazide right before bedtime.

Hydrochlorothiazide is utilized for the treatment of high blood pressure. It is also prescribed to address swelling resulting from conditions such as heart failure, liver damage (cirrhosis), and the use of corticosteroids or estrogens. Additionally, it may help manage swelling associated with kidney problems.

In most instances, patients on higher doses of hydrochlorothiazide have a greater risk of experiencing adverse reactions. One notable effect is hyperglycemia, characterized by elevated fasting blood glucose levels.

The use of diuretics like hydrochlorothiazide is prohibited in certain contexts, as they can be used to flush drugs out of a person’s system, potentially aiding in passing a urine drug test. Organizations such as the World Anti-Doping Agency (WADA) ban the use of diuretics for this reason. It’s important to recognize that drug abuse and addiction are complex issues, often extending beyond merely achieving a ‘high.’

Hydrochlorothiazide is contraindicated for individuals with kidney diseases due to the added stress it can place on the kidneys. It should also be avoided by those with a history of liver diseases, diabetes, low blood potassium levels, and decreased blood sodium levels.

The use of hydrochlorothiazide can potentially worsen heart and kidney damage, particularly in individuals with a history of stimulant medication misuse. Additionally, hydrochlorothiazide may interact with other drugs, including lithium and digoxin, which are used to treat heart damage and failure.

As of August 20, 2020, the U.S. Food and Drug Administration has approved revisions to the hydrochlorothiazide (HCTZ) drug label. These revisions aim to inform healthcare professionals and patients about a slightly increased risk of non-melanoma skin cancer (basal cell skin cancer or squamous cell skin cancer) associated with HCTZ use and to encourage awareness.

Certain foods should be avoided or consumed in moderation while taking diuretics like hydrochlorothiazide. These include frozen meals, canned or pickled foods, and snack foods such as chips, pretzels, and popcorn, all of which are often high in salt.

Pfizer is set to withdraw six batches of Accuretic tablets, one batch of quinapril and hydrochlorothiazide tablets, and four batches of quinapril HCI/hydrochlorothiazide tablets. According to health officials, nitrosamines can be present in water, various foods including cured and grilled meats, dairy products, and vegetables.

Chlorthalidone is a more potent and enduring antihypertensive medication compared to hydrochlorothiazide, the most frequently prescribed medication. However, it may also cause a more pronounced reduction in serum potassium levels.

Lannett Company Inc. is recalling 25,680 bottles of triamterene and hydrochlorothiazide capsules due to samples failing to meet impurity and degradation specifications during routine testing. This recall is listed in the January 25, 2023, US Food and Drug Administration (FDA) Enforcement Report.

While hydrochlorothiazide is the most commonly used thiazide diuretic, it’s important to note that liver injury associated with thiazide diuretics is exceedingly rare. This is despite their structural similarity, suggesting that liver injury may not be a class-wide effect.

Discontinuing hydrochlorothiazide should only be done under the guidance of your doctor. They may recommend tapering off the medication gradually to minimize potential side effects. Stopping high blood pressure medication without medical supervision can have adverse consequences.

Hair loss is an uncommon side effect reported in studies of hydrochlorothiazide. Hair thinning may occur, but extensive hair loss is not typically associated with this medication.

In some cases, an effective dose of hydrochlorothiazide for blood pressure control was found to be 50 mg/day in 52% of responders, leading to an average weight loss of 1.58 kg. An additional 29% achieved target blood pressure with similar weight loss but required a higher dose, typically 100 mg/day.