Used for Hypertension

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Manufactured by various FDA-approved generic manufacturers.

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Updated on 24 Apr 2024

Learn more about hydrochlorothiazide

What dosages is hydrochlorothiazide available in?

What dosages is hydrochlorothiazide available in?

hydrochlorothiazide is available as a 12.5 mg capsule.

What is hydrochlorothiazide used for?

What is hydrochlorothiazide used for?

hydrochlorothiazide is a thiazide diuretic that is used to treat:

  • High blood pressure
  • Swelling in the body from fluids (edema), in addition to other medications
How does hydrochlorothiazide work?

How does hydrochlorothiazide work?

hydrochlorothiazide is a thiazide diuretic, also known as a water pill, that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, like sodium and potassium, to lower blood pressure and reduce swelling.

How do I take hydrochlorothiazide?

How do I take hydrochlorothiazide?

hydrochlorothiazide is typically started at 12.5 mg by mouth once daily whether given alone or in combination with other antihypertensives. Total daily doses greater than 50 mg are not recommended.

Is it safe for me to take hydrochlorothiazide?

Is it safe for me to take hydrochlorothiazide?

hydrochlorothiazide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have anuria or a hypersensitivity to this product or other sulfonamide derived drugs.

hydrochlorothiazide Common Side Effects

hydrochlorothiazide Common Side Effects

Common side effects of hydrochlorothiazide:

  • Dizziness
  • Weakness
  • Skin more sensitive to sunlight
  • Temporary blurred vision
  • Headache
  • Low blood pressure
  • Electrolytes out of balance
  • Difficulty getting or maintaining an erection
hydrochlorothiazide Serious Side Effects

hydrochlorothiazide Serious Side Effects

Serious side effects are rare with hydrochlorothiazide. Contact your healthcare provider immediately if you experience any of the following.

  • Serious skin allergic reaction: painful blisters, peeling rash, flu-like symptoms
  • Inflammation of the pancreas (pancreatitis): pain, swelling, or tenderness in the stomach, fever, nausea, vomiting, fast heartbeat
Effects of other drugs, drug classes and over-the-counter products on hydrochlorothiazide

Effects of other drugs, drug classes and over-the-counter products on hydrochlorothiazide

The following medications may interact with hydrochlorothiazide:

  • Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur
  • Antidiabetic drugs (oral agents and insulin) dosage adjustment of the antidiabetic drug may be required
  • Other antihypertensive drugs: Additive effect or potentiation
  • Cholestyramine and colestipol resins: Cholestyramine and colestipol resins bind the hydrochlorothiazide and reduce its absorption
  • Corticosteroid, ACTH: Possible electrolyte depletion, particularly hypokalemia
  • Pressor amines (e.g., norepinephrine): Possible decreased response to pressor amines
  • Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant
  • Lithium: Generally should not be given with diuretics
  • Non-steroidal anti-inflammatory drugs: May reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics
Who makes hydrochlorothiazide?

Who makes hydrochlorothiazide?

Various FDA-approved generic manufacturers

Is hydrochlorothiazide safe in pregnancy?

Is hydrochlorothiazide safe in pregnancy?

It is not known if hydrochlorothiazide will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.


What to do if you missed your hydrochlorothiazide dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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