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Hydrochlorothiazide is available as a 12.5 mg capsule.

Hydrochlorothiazide is a thiazide diuretic that is used to treat:

• High blood pressure
• Swelling in the body from fluids (edema), in addition to other medications

Hydrochlorothiazide is a thiazide diuretic, also known as a water pill, that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, like sodium and potassium, to lower blood pressure and reduce swelling.

Hydrochlorothiazide is typically started at 12.5 mg by mouth once daily whether given alone or in combination with other antihypertensives. Total daily doses greater than 50 mg are not recommended.

Hydrochlorothiazide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have anuria or a hypersensitivity to this product or other sulfonamide derived drugs.

Common side effects of Hydrochlorothiazide:

• Dizziness
• Weakness
• Skin more sensitive to sunlight
• Temporary blurred vision
• Headache
• Low blood pressure
• Electrolytes out of balance
• Difficulty getting or maintaining an erection

Serious side effects are rare with Hydrochlorothiazide. Contact your healthcare provider immediately if you experience any of the following.

• Serious skin allergic reaction: painful blisters, peeling rash, flu-like symptoms
• Inflammation of the pancreas (pancreatitis): pain, swelling, or tenderness in the stomach, fever, nausea, vomiting, fast heartbeat

The following medications may interact with Hydrochlorothiazide:

• Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur
• Antidiabetic drugs (oral agents and insulin) dosage adjustment of the antidiabetic drug may be required
• Other antihypertensive drugs: Additive effect or potentiation
• Cholestyramine and colestipol resins: Cholestyramine and colestipol resins bind the Hydrochlorothiazide and reduce its absorption
• Corticosteroid, ACTH: Possible electrolyte depletion, particularly hypokalemia
• Pressor amines (e.g., norepinephrine): Possible decreased response to pressor amines
• Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant
• Lithium: Generally should not be given with diuretics
• Non-steroidal anti-inflammatory drugs: May reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics

Various FDA-approved generic manufacturers

It is not known if Hydrochlorothiazide will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.

• Microzide