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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

methylprednisolone Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is methylprednisolone available in?

What dosages is methylprednisolone available in?

methylprednisolone is available as a 4 mg, 8 mg, 16 mg, and 32 mg oral tablet.

What is methylprednisolone used for?

What is methylprednisolone used for?

methylprednisolone is a corticosteroid that is used to treat the following:

  • Conditions affecting certain hormones (e.g., low adrenal hormones)
  • Joint conditions (e.g., rheumatoid arthritis)
  • Lupus
  • Skin conditions (e.g., Stevens-Johnson syndrome)
  • Allergic reactions
  • Eye inflammation
  • Lung problems
  • Conditions related to blood cells
  • Cancer of blood cells (e.g., leukemia)
  • Gut conditions (e.g., ulcerative colitis)
  • Multiple sclerosis
How does methylprednisolone work?

How does methylprednisolone work?

methylprednisolone is a corticosteroid. It’s a lab-made medication that’s similar to cortisol, a natural stress hormone your body makes. Methylprednisolone (methylprednisolone) works by calming down your body’s immune response, which can help get rid of certain medical problems that are caused by a sensitive immune system. In addition, methylprednisolone (methylprednisolone) lowers the amount of inflammatory chemicals that cause pain, redness, itching, and swelling.

How do I take methylprednisolone?

How do I take methylprednisolone?

In general, the dose of methylprednisolone depends on the condition that you’re taking the medication for and how serious it is. Your provider will raise or lower your dose based on how you respond to this medication and if you have any side effects.
The typical starting dose of methylprednisolone can range from 4 mg to 48 mg by mouth per day.

Is it safe for me to take methylprednisolone?

Is it safe for me to take methylprednisolone?

methylprednisolone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a systemic fungal infection or a known hypersensitivity to methylprednisolone.

methylprednisolone Common Side Effects

methylprednisolone Common Side Effects

Common side effects of methylprednisolone:

  • Swelling
  • Muscle weakness
  • Stomach pain
  • Bloating
  • Increased appetite
  • Trouble sleeping
  • Weight gain
  • Dizziness
methylprednisolone Serious Side Effects

methylprednisolone Serious Side Effects

Serious side effects are rare with methylprednisolone. Contact your healthcare provider immediately if you experience any of the following.

  • Withdrawal symptoms: Long-term fatigue, muscle weakness, poor appetite, weight loss, belly pain
Effects of other drugs, drug classes and over-the-counter products on methylprednisolone

Effects of other drugs, drug classes and over-the-counter products on methylprednisolone

The following medications may interact with methylprednisolone:

  • Mutual inhibition of metabolism occurs with concurrent use of cyclosporin and methylprednisolone; therefore, it is possible that adverse events associated with the individual use of either drug may be more likely to occur
  • methylprednisolone may increase the clearance of chronic high dose aspirin. This could lead to decreased salicylate serum levels or increase the risk of salicylate toxicity when methylprednisolone is withdrawn. Aspirin should be used cautiously in conjunction with corticosteroids in patients suffering from hypoprothrombinemia
  • The effect of methylprednisolone on oral anticoagulants is variable. There are reports of enhanced as well as diminished effects of anticoagulant when given concurrently with corticosteroids. Therefore, coagulation should be monitored to maintain the desired anticoagulant effect
Who makes methylprednisolone?

Who makes methylprednisolone?

Various FDA-approved generic manufacturers

Is methylprednisolone safe in pregnancy?

Is methylprednisolone safe in pregnancy?

It is not known if methylprednisolone will harm your unborn baby. Animal studies, however, suggest that excessive use of steroids can cause harm to unborn babies. You should talk to your healthcare provider before taking this medication if you are pregnant.


What to do if you missed your methylprednisolone dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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