MethylprednisolonePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Methylprednisolone
    Generic for Medrol
    2 tablets $9 USD
    Save $44.36
  3. Methylprednisolone
    Generic for Medrol
    12 tablets $33.3 USD
    Save $286.86
  4. Methylprednisolone
    Generic for Medrol
    18 tablets $49.8 USD
    Save $430.44
  5. Methylprednisolone
    Generic for Medrol
    28 tablets $80.4 USD
    Save $666.64
  6. Methylprednisolone
    Generic for Medrol
    21 blister pack of tabletss $5.74 USD
    Save $20.94
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Do you need a prescription for methylprednisolone?

Yes, methylprednisolone is only available with a valid physician Rx.

How much is methylprednisolone without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase methylprednisolone, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for methylprednisolone in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a methylprednisolone savings card?

Yes. Save up to 90% on your methylprednisolone with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a methylprednisolone coupon provider in the US?

No. Now Patient does not provide methylprednisolone coupons or FREE methylprednisolone samples.

Do you accept commercial, Medicare or Medicaid coverage for methylprednisolone in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much methylprednisolone?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using methylprednisolone. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much methylprednisolone. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of methylprednisolone and manufacturer

Methylprednisolone is available in the US under various brand names, including Medrol, Solu-Medrol, and Depo-Medrol. These brands are manufactured by different pharmaceutical companies.

UK brand name of methylprednisolone and manufacturer

Methylprednisolone is available in the UK under various brand names, including Medrone, Depo-Medrone, and others. These brands are manufactured by different pharmaceutical companies.

Prescription requirement for methylprednisolone

Methylprednisolone is a prescription medication in both the US and the UK. It is not available over the counter and requires a prescription from a healthcare provider.

FDA approval of methylprednisolone

Methylprednisolone has received FDA approval for various medical conditions, including inflammatory and allergic disorders, certain types of arthritis, asthma, and certain types of cancer.

Is methylprednisolone available in the UK on NHS?

Methylprednisolone is available on the NHS in the UK. It can be prescribed by healthcare providers for the treatment of specific medical conditions.

Mechanism of action

Methylprednisolone belongs to a class of medications known as corticosteroids. It works by reducing inflammation and suppressing the immune system response in the body. It has potent anti-inflammatory and immunosuppressive effects.

Uses of methylprednisolone

Methylprednisolone is a glucocorticoid used to treat a variety of medical conditions, including:

  • Inflammatory and allergic disorders: It is commonly prescribed for conditions such as rheumatoid arthritis, lupus, asthma, severe allergic reactions, and inflammatory bowel disease
  • Joint and muscle conditions: It may be used for the treatment of certain joint and muscle conditions, including osteoarthritis, tendinitis, and bursitis
  • Skin conditions: It can be prescribed for certain skin conditions, such as eczema, psoriasis, and allergic dermatitis
  • Certain types of cancer: Methylprednisolone may be used as part of cancer treatment regimens, particularly for certain types of lymphomas and leukemias

Dosage of methylprednisolone

Your dose of methylprednisolone will vary depending on the specific condition being treated, the severity of symptoms, and individual patient factors. It is important to follow the dosage instructions and medical advice provided by your healthcare provider.

Precautions and warnings for methylprednisolone

  • Methylprednisolone tablets should not be used in individuals who have a known allergy to the medication or any of its components
  • Methylprednisolone can interact with certain medications and may increase the risk of side effects. It is important to inform your healthcare provider about all the medications you are taking
  • Long-term use of methylprednisolone should be done under the guidance of a healthcare provider, as it may cause various side effects
  • Tell your doctor your medical history, especially if you have osteoporosis, diabetes, cataracts, glaucoma, herpes eye infection, heart disease such as congestive heart failure, high blood pressure (hypertension), psychosis, anxiety, intestinal problems (such as peptic ulcer, ulcerative colitis), or seizures
  • Tell your doctor if you are pregnant, planning to become pregnant, or are breast-feeding

Side effects of methylprednisolone

Common adverse effects of methylprednisolone may include increased appetite, weight gain, insomnia, mood changes, and increased susceptibility to infections. It can also cause more serious side effects, such as high blood pressure, increased blood sugar levels, osteoporosis, and adrenal gland suppression. Very serious life-threatening reactions to methylprednisolone are rare. However, get help immediately if you develop a rash, itching, swelling of the face, tongue, or throat, or have trouble breathing.

Interactions with other drugs

Methylprednisolone may have drug interactions with certain medications, including live vaccines such as nasal flu, chickenpox, smallpox, and measles, mumps, and rubella vaccine, anticoagulants, azole antifungals (such as ketoconazole), cyclosporine, macrolide antibiotics (such as erythromycin), St. John’s wort, and some drugs used for the treatment of seizures (such as phenytoin, and phenobarbital), and rifampin. It is important to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter supplements and vitamins, to avoid potential interactions.

Similar drugs to methylprednisolone

Other medications similar to methyprednisolone include prednisolone, prednisone, and hydrocortisone.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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