methylnaltrexone bromide
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Manufactured by various FDA-approved generic manufacturers.
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methylnaltrexone bromide Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is methylnaltrexone bromide available in?
methylnaltrexone bromide is available as a 150 mg oral tablet and a 8 mg/0.4 mL single-dose pre-filled syringe. or 12 mg/0.6 mL single-dose pre-filled syringe or single-dose vial.
What is methylnaltrexone bromide used for?
methylnaltrexone bromide is an opioid antagonist and is used to treat constipation due to opioid pain medications.
How does methylnaltrexone bromide work?
methylnaltrexone bromide is an opioid antagonist, which means that it blocks the opioid receptors in the intestines so that you can go to the bathroom more easily.
How do I take methylnaltrexone bromide?
methylnaltrexone bromide is dosed as follows:
- Pill form: Take 450 mg by mouth once daily in the morning
- Injection form: The typical dose is 12 mg injected subcutaneously (under the skin) once daily. If you are taking methylnaltrexone bromide (methylnaltrexone) for advanced illness, the dose may be lower or higher depending on your weight, and can be taken every other day as needed for constipation (but use no more than 1 dose in a 24-hour period)
Is it safe for me to take methylnaltrexone bromide?
methylnaltrexone bromide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known or suspected mechanical gastrointestinal obstruction and at increased risk of recurrent obstruction.
methylnaltrexone bromide Common Side Effects
Common side effects of methylnaltrexone bromide:
- Abdominal pain
- Diarrhea
- Nausea
methylnaltrexone bromide Serious Side Effects
Serious side effects are rare with methylnaltrexone bromide. Contact your healthcare provider immediately if you experience any of the following.
- Severe abdominal pain, which may be a symptom of stomach or intestine injury
- Severe diarrhea
Effects of other drugs, drug classes and over-the-counter products on methylnaltrexone bromide
The following medications may interact with methylnaltrexone bromide:
- Other opioid antagonists: Potential for additive effect and increased risk of opioid withdrawal; avoid concomitant use
Who makes methylnaltrexone bromide?
Various FDA-approved generic manufacturers
Is methylnaltrexone bromide safe in pregnancy?
Taking methylnaltrexone bromide during pregnancy may cause opioid withdrawal symptoms in your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with methylnaltrexone bromide.
What to do if you missed your methylnaltrexone bromide dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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