leflunomide
Are you tired of high medication costs? Our service offers unbeatable savings on your leflunomide prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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leflunomide key facts
What dosages is leflunomide available in?
leflunomide is available as a 10 mg, 20 mg, and 100 mg oral tablet.
What is leflunomide used for?
leflunomide is a non-biologic, disease-modifying antirheumatic drug (DMARD) that is used to treat adults with active rheumatoid arthritis.
How does leflunomide work?
leflunomide is a pyrimidine synthesis inhibitor. It blocks certain proteins and cells of the immune system that are overactive from turning on. This lowers inflammation in the joints, which helps treat symptoms and prevent joint damage in people with rheumatoid arthritis.
How do I take leflunomide?
leflunomide is typically taken as a : 100 mg dose by mouth daily for 3 days and then 20 mg daily thereafter.
Is it safe for me to take leflunomide?
leflunomide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you are pregnant, have severe hepatic impairment, or are currently taking teriflunomide.
leflunomide Common Side Effects
Common side effects of leflunomide include:
- Diarrhea
- Headache
- Nausea
- Rash
- Abnormal liver labs
- Hair thinning or hair loss
- High blood pressure
leflunomide Serious Side Effects
Serious side effects are rare with leflunomide. Contact your healthcare provider immediately if you experience any of the following.
- Liver problems: nausea, vomiting, stomach pain, swelling of your stomach, yellowing of your skin or the whites of your eyes, clay-colored stool, confusion
- Serious infections: fever, difficulty breathing, weakness, cough, sweating, chills, stomach pain, diarrhea, burning when you urinate, urinating more often
- Serious allergic reactions and skin reactions: sore throat, fever, fatigue, rash, hives, painful blisters, skin reddening, skin peeling, swollen lymph nodes
Effects of other drugs, drug classes and over-the-counter products on leflunomide
The following medications may interact with leflunomide:
- Drugs metabolized by CYP2C8 and OAT3 transporters – May increase the levels of these drugs
- Oral contraceptives – May increase levels of ethinylestradiol and levonorgestrel
- Drugs metabolized by CYP1A2 – May decrease the levels of these drugs.
- Warfarin: Monitor INR as INR may be decreased
- Drugs metabolized by BCRP and OATP1B1/B3 transporters: May increase levels of these drugs
- Rosuvastatin: The dose of rosuvastatin should not exceed 10 mg once daily in patients taking
- leflunomide
Who makes leflunomide?
Various FDA-approved generic manufacturers
Is leflunomide safe in pregnancy?
leflunomide may cause harm to your unborn baby. You should take a pregnancy test before starting this medication. Use effective contraception if you can become pregnant during treatment and during a drug elimination procedure. Stop leflunomide and use an accelerated drug elimination procedure if you become pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my leflunomide prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your leflunomide prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient leflunomide savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient leflunomide savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for leflunomide | Canadian Prescription Savings* for leflunomide | leflunomide Drug Coupon* | leflunomide Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of leflunomide?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for leflunomide | Canadian Prescription Savings* for leflunomide | leflunomide Drug Coupon* | leflunomide Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the leflunomide savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the leflunomide drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for leflunomide, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the leflunomide prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, leflunomide is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed leflunomide for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the leflunomide prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the leflunomide prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for leflunomide
If you are having trouble paying for your leflunomide medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for leflunomide you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- leflunomide is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers leflunomide
- If leflunomide is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for leflunomide
If you are having trouble paying for your leflunomide medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for leflunomide you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers leflunomide
- If leflunomide is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for leflunomide
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your leflunomide treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for leflunomide you will need to meet the following criteria:
- You must be currently insured and have coverage for leflunomide
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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NowPatient is owned and operated by Infohealth Ltd, a licensed online pharmacy with services spanning the UK, US and Rest of the World. Infohealth Ltd is registered in England and Wales under company number 04004930 and our registered office is at Lynwood House, 373 – 375 Station Road, Harrow, England, HA1 2AW.
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Can you tell me more about your NHS online pharmacy?
NowPatient’s Pharmaceutical services in the UK are provided by Infohealth Limited trading as ‘Infohealth Pharmacy’.
Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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NowPatient prescribing services are run by Infohealth Limited. The Clinical Safety Officer and nominated individual is Mr Navin Khosla.
Can you tell me more about NowPatient’s US services?
Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
Is NowPatient legit and can I trust information from NowPatient?
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