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Lamictal ODT is the brand name for lamotrigine and is available as an orally disintegrating tablet.

Lamictal ODT is available as a 25 mg, 50 mg, 100 mg, and 200 mg orally disintegrating tablet.

Lamictal ODT is an antiepileptic that is used to treat seizures (partial seizures, tonic-clonic seizures), seizures of Lennox-Gastaut syndrome, and bipolar disorder.

Lamictal ODT is an antiepileptic. It’s not exactly clear how this medication works to manage seizures and treat bipolar disorder.
For seizures, research suggests that lamotrigine (Lamictal) can block and prevent your brain from sending certain chemicals or signals that can overly excite your nerves. This helps lower bursts of activity in your brain, which can prevent seizures.

Lamictal ODT is typically started at a low dose, and the dose will be raised in the following weeks. The dose depends on what you’re taking lamotrigine (Lamictal) for, your age, and the other medications that you’re taking. Your dose might also differ if you have kidney or liver problems. The typical maintenance dose ranges from 100 mg to 500 mg per day, split into 1 or 2 doses throughout the day.

Lamictal ODT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to the drug or its ingredients.

Common side effects of Lamictal ODT:
Dizziness
Headache
Double vision
Loss of coordination
Nausea
Blurry vision
Sleepiness
Stuffy nose
Sore throat
Rash

Serious side effects are rare with Lamictal ODT. Contact your healthcare provider immediately if you experience any of the following.

Severe allergic or skin reaction: rash, blistering or peeling of skin, hives, painful sores in your mouth or around your eyes, fever, trouble breathing, swollen lymph nodes
Overactive immune system: fever, rash, belly pain or swelling, brown urine, yellowing of the whites of the eyes or skin
Irregular heartbeat
Suicidal thoughts and behavior
Meningitis (brain inflammation): stiff neck, rash, fever, light sensitivity, headache, chills, nausea, vomiting

The following medications may interact with Lamictal ODT:
Valproate increases lamotrigine concentrations more than 2-fold.
Carbamazepine, phenytoin, phenobarbital, primidone, and rifampin decrease lamotrigine concentrations by approximately 40%.
Estrogen-containing oral contraceptives decrease lamotrigine concentrations by approximately 50%.
Protease inhibitors lopinavir/ritonavir and atazanavir/lopinavir decrease lamotrigine exposure by approximately 50% and 32%, respectively.
Coadministration with organic cationic transporter 2 substrates with narrow therapeutic index is not recommended.

GlaxoSmithKline

Lamictal ODT may cause harm to your unborn baby based on animal studies. You should talk to your healthcare provider before taking this medication if you are pregnant. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to AEDs, including Lamictal ODT, during pregnancy. Encourage women who are taking Lamictal ODT during pregnancy to enroll in the North American Antiepileptic Drug (NAAED)
Pregnancy Registry by calling 1-888-233-2334 or visiting http://www.aedpregnancyregistry.org/.

• Lamotrigine