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Istalol is the brand name for timolol maleate ophthalmic solution.

Istalol is available as a 0.5% ophthalmic solution.

Istalol is a beta blocker and is used to treat high pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma).

Istalol is a beta blocker that lowers the amount of fluid in the eye. When there’s less fluid inside the eye, the eye pressure goes down.

The typical dose is 1 drop in the affected eye(s) once daily in the morning.

Istalol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Bronchial asthma, a history of bronchial asthma, severe chronic obstructive
pulmonary disease.
Sinus bradycardia, second or third degree atrioventricular block, overt
cardiac failure, cardiogenic shock.
Hypersensitivity to any component of this product.

Common side effects of Istalol:

• Temporary burning or stinging in the eye after using

Serious side effects are rare with Istalol. Contact your healthcare provider immediately if you experience any of the following.

Trouble breathing: shortness of breath, wheezing, chest tightness
Heart failure: shortness of breath; fatigue; swelling in the legs, ankles and feet
Allergic reactions: rash around your eyes or face, closing of the throat, hives, swelling

The following medications may interact with Istalol:

• Concomitant use with systemic beta-blockers may potentiate systemic betablockade.
• Oral or intravenous calcium antagonists may cause atrioventricular
• conduction disturbances, left ventricular failure, and hypotension.
• Catecholamine-depleting drugs may have additive effects and produce
• hypotension and/or marked bradycardia.
• Digitalis and calcium antagonists may have additive effects in prolonging
• atrioventricular conduction time.
• Potentiated systemic beta-blockade (e.g., decreased heart rate) has been
• reported during combined treatment with Quinidine and timolol.

Bausch Health

There are no adequate and well-controlled studies in pregnant women. Istalol should be
used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Timolol Maleate