Irbesartan-hydrochlorothiazidePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Irbesartan-Hydrochlorothiazide
    Generic for Avalide
    30 tablets $9 USD
    Save $58.80
  3. Irbesartan-Hydrochlorothiazide
    Generic for Avalide
    40 tablets $11.4 USD
    Save $79.00
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Do you need a prescription for irbesartan-hydrochlorothiazide?

Yes, irbesartan-hydrochlorothiazide is only available with a valid physician Rx.

How much is irbesartan-hydrochlorothiazide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase irbesartan-hydrochlorothiazide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for irbesartan-hydrochlorothiazide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a irbesartan-hydrochlorothiazide savings card?

Yes. Save up to 90% on your irbesartan-hydrochlorothiazide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a irbesartan-hydrochlorothiazide coupon provider in the US?

No. Now Patient does not provide irbesartan-hydrochlorothiazide coupons or FREE irbesartan-hydrochlorothiazide samples.

Do you accept commercial, Medicare or Medicaid coverage for irbesartan-hydrochlorothiazide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much irbesartan-hydrochlorothiazide?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using irbesartan-hydrochlorothiazide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much irbesartan-hydrochlorothiazide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic irbesartan-hydrochlorothiazide?

Generic Irbesartan-hydrochlorothiazide refers to the non-brand-name version of the medication. It contains the same active ingredients as the brand-name drug but is typically less expensive.

FDA approval of irbesartan-hydrochlorothiazide

Irbesartan-hydrochlorothiazide is approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension (high blood pressure).

Active ingredients of irbesartan-hydrochlorothiazide

The active ingredients of irbesartan-hydrochlorothiazide are irbesartan and hydrochlorothiazide.

US brand name of irbesartan-hydrochlorothiazide and manufacturer

Irbesartan-hydrochlorothiazide is available in the US under various brand names, including Avalide and generic versions. It is manufactured by different pharmaceutical companies.

UK brand name of irbesartan-hydrochlorothiazide and manufacturer

In the UK, irbesartan-hydrochlorothiazide is available under various brand names, including CoAprovel and generic versions. The manufacturer may vary depending on the brand name.

Prescription requirement for irbesartan-hydrochlorothiazide

A prescription (Rx) is required for irbesartan-hydrochlorothiazide in both the US and the UK.

Availability of irbesartan-hydrochlorothiazide in the UK with NHS prescription

Irbesartan-hydrochlorothiazide is available in the UK with an NHS prescription.

Conditions treated by irbesartan-hydrochlorothiazide

Irbesartan-hydrochlorothiazide is an antihypertensive agent used for the treatment of high blood pressure (hypertension) and heart failure and to reduce the risk of heart attack and stroke in certain individuals with heart disease. It may also be used to treat diabetic nephropathy (kidney disease in patients with diabetes and high blood pressure).

How does irbesartan-hydrochlorothiazide work?

Irbesartan-hydrochlorothiazide works through two mechanisms. Irbesartan is an angiotensin receptor blocker (ARB) that blocks the action of a hormone called angiotensin II, which constricts blood vessels and raises blood pressure. Hydrochlorothiazide is a thiazide diuretic that increases the excretion of salt and water from the body, helping to reduce fluid retention and lower blood pressure.

Forms of irbesartan-hydrochlorothiazide available

Irbesartan-hydrochlorothiazide is available in the form of oral tablets.

Dosage of irbesartan-hydrochlorothiazide

The dose of irbesartan-hydrochlorothiazide may vary depending on the individual’s condition, medical history, and response to the medication. It is important to follow the recommended dosage instructions provided by the healthcare professional.

Directions for irbesartan-hydrochlorothiazide use

Irbesartan-hydrochlorothiazide should be taken exactly as directed by the healthcare provider. The tablets are usually taken orally, with or without food. It is important to swallow the tablets whole and avoid crushing or chewing them. If you are taking cholestyramine or colestipol to lower your cholesterol, take irbesartan/hctz at least 4 hours before or 4 to 6 hours after.

Warnings and precautions for irbesartan-hydrochlorothiazide

  • Irbesartan-hydrochlorothiazide may cause certain side effects, including dizziness, low blood pressure, and electrolyte imbalances. It may also have interactions with other medications. Inform the healthcare provider about all medications being taken
  • Tell your doctor if you have kidney disease, liver disease, high blood potassium levels, or skin cancer before you start taking this medication
  • Regular monitoring of blood pressure, blood sugar levels, and kidney function may be required during treatment

Use of irbesartan-hydrochlorothiazide during pregnancy and breastfeeding

The use of irbesartan-hydrochlorothiazide during pregnancy is not recommended, especially during the second and third trimesters, as it may cause harm to the unborn baby. It should be avoided in breastfeeding mothers as well, as hydrochlorothiazide can pass into breast milk.

Possible side effects of irbesartan-hydrochlorothiazide

In clinical trials common side effects of irbesartan-hydrochlorothiazide may include dizziness, lightheadedness, headache, joint and back pain, fatigue, cough, hypotension, renal dysfunction, eye pain, vision loss, and high potassium levels (hyperkalemia). If these adverse events persist or worsen, it is important to contact a healthcare provider. Get medical help right away if you have a serious side effects such as an allergic reaction. Symptoms include hives, trouble breathing, worsening shortness of breath, sore throat, chest pain, swelling of the face, tongue or throat, skin rash, blisters, and serious skin reactions.

Interactions with other drugs

Irbesartan-hydrochlorothiazide may interact with other medications, including aliskiren, lithium, beta blockers, carbamazepine, angiotensin-converting enzyme (ACEinhibitors) inhibitors such as captopril, enalapril, and lisinopril, other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen and naproxen, diuretics such as amiloride, other medications to treat high blood pressure such as amlodipine, potassium supplements, and ritonavir. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, herbal products, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to irbesartan-hydrochlorothiazide

Other combination medications used for the treatment of hypertension include amlodipine and hydrochlorothiazide, and lisinopril and hydrochlorothiazide.


Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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