Used for Hypertension

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Updated on 24 Apr 2024

irbesartan/hydrochlorothiazide Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is irbesartan/hydrochlorothiazide available in?

What dosages is irbesartan/hydrochlorothiazide available in?

irbesartan/hydrochlorothiazide is available as an oral tablet that contains 150 mg irbesartan/12.5 mg hydrochlorothiazide or 300 mg irbesartan/12.5 mg hydrochlorothiazide.

What is irbesartan/hydrochlorothiazide used for?

What is irbesartan/hydrochlorothiazide used for?

irbesartan/hydrochlorothiazide is a combination medication that’s used to treat high blood pressure.

How does irbesartan/hydrochlorothiazide work?

How does irbesartan/hydrochlorothiazide work?

irbesartan/hydrochlorothiazide is a combination of irbesartan and hydrochlorothiazide. Irbesartan is an angiotensin II receptor blocker (ARB), which blocks a chemical that tightens your blood vessels. This causes your blood vessels to relax and allows more blood and oxygen to reach the heart and other parts of your body.
Hydrochlorothiazide is a thiazide diuretic (water pill) that makes you urinate more. It lowers blood pressure by working in your kidneys to get rid of extra water and electrolytes, like sodium, chloride, and potassium.

How do I take irbesartan/hydrochlorothiazide?

How do I take irbesartan/hydrochlorothiazide?

irbesartan/hydrochlorothiazide is typically taken by mouth once daily.

Is it safe for me to take irbesartan/hydrochlorothiazide?

Is it safe for me to take irbesartan/hydrochlorothiazide?

irbesartan/hydrochlorothiazide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have anuria (you aren’t producing urine) or a hypersensitivity to sulfonamide-derived drugs. You should also not take aliskiren along with irbesartan/hydrochlorothiazide if you have diabetes.

irbesartan/hydrochlorothiazide Common Side Effects

irbesartan/hydrochlorothiazide Common Side Effects

Common side effects of irbesartan/hydrochlorothiazide include:

  • Dizziness
  • Tiredness
  • Muscle pain
irbesartan/hydrochlorothiazide Serious Side Effects

irbesartan/hydrochlorothiazide Serious Side Effects

Serious side effects are rare with irbesartan/hydrochlorothiazide. Contact your healthcare provider immediately if you experience any of the following.

  • Kidney problems: Difficulties urinating, swelling in your legs or feet, tiredness, confusion, nausea
  • Electrolyte imbalance: Dry mouth, weakness, tiredness, dizziness, muscle pain or cramps, irregular heart beat, vomiting, or nausea
  • Allergic reaction: Rash, hives, difficulty breathing, difficulty swallowing, or swelling of the face, lips, or throat
Effects of other drugs, drug classes and over-the-counter products on irbesartan/hydrochlorothiazide

Effects of other drugs, drug classes and over-the-counter products on irbesartan/hydrochlorothiazide

The following medications may interact with irbesartan/hydrochlorothiazide:

  • NSAIDs and selective COX-2 inhibitors – Can reduce diuretic, natriuretic of diuretic and may lead to increased risk of kidney impairment and reduced antihypertensive effect
  • Antidiabetic drugs – Dosage adjustment of antidiabetic may be required.
  • Cholestyramine and colestipol – Reduced absorption of thiazides
  • Lithium – Increases in serum lithium concentrations and lithium toxicity
  • Carbamazepine – Increased risk of hyponatremia
Who makes irbesartan/hydrochlorothiazide?

Who makes irbesartan/hydrochlorothiazide?

Various FDA-approved generic manufacturers

Is irbesartan/hydrochlorothiazide safe in pregnancy?

Is irbesartan/hydrochlorothiazide safe in pregnancy?

irbesartan/hydrochlorothiazide may cause harm to your unborn baby and should be discontinued as soon as possible if you become pregnant.


What to do if you missed your irbesartan/hydrochlorothiazide dose

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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