irbesartan/hydrochlorothiazide
Used for Hypertension
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your irbesartan/hydrochlorothiazide more affordable.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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irbesartan/hydrochlorothiazide key facts
What dosages is irbesartan/hydrochlorothiazide available in?
irbesartan/hydrochlorothiazide is available as an oral tablet that contains 150 mg irbesartan/12.5 mg hydrochlorothiazide or 300 mg irbesartan/12.5 mg hydrochlorothiazide.
What is irbesartan/hydrochlorothiazide used for?
irbesartan/hydrochlorothiazide is a combination medication that’s used to treat high blood pressure.
How does irbesartan/hydrochlorothiazide work?
irbesartan/hydrochlorothiazide is a combination of irbesartan and hydrochlorothiazide. Irbesartan is an angiotensin II receptor blocker (ARB), which blocks a chemical that tightens your blood vessels. This causes your blood vessels to relax and allows more blood and oxygen to reach the heart and other parts of your body.
Hydrochlorothiazide is a thiazide diuretic (water pill) that makes you urinate more. It lowers blood pressure by working in your kidneys to get rid of extra water and electrolytes, like sodium, chloride, and potassium.
How do I take irbesartan/hydrochlorothiazide?
irbesartan/hydrochlorothiazide is typically taken by mouth once daily.
Is it safe for me to take irbesartan/hydrochlorothiazide?
irbesartan/hydrochlorothiazide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take this medication if you have anuria (you aren’t producing urine) or a hypersensitivity to sulfonamide-derived drugs. You should also not take aliskiren along with irbesartan/hydrochlorothiazide if you have diabetes.
irbesartan/hydrochlorothiazide Common Side Effects
Common side effects of irbesartan/hydrochlorothiazide include:
- Dizziness
- Tiredness
- Muscle pain
irbesartan/hydrochlorothiazide Serious Side Effects
Serious side effects are rare with irbesartan/hydrochlorothiazide. Contact your healthcare provider immediately if you experience any of the following.
- Kidney problems: Difficulties urinating, swelling in your legs or feet, tiredness, confusion, nausea
- Electrolyte imbalance: Dry mouth, weakness, tiredness, dizziness, muscle pain or cramps, irregular heart beat, vomiting, or nausea
- Allergic reaction: Rash, hives, difficulty breathing, difficulty swallowing, or swelling of the face, lips, or throat
Effects of other drugs, drug classes and over-the-counter products on irbesartan/hydrochlorothiazide
The following medications may interact with irbesartan/hydrochlorothiazide:
- NSAIDs and selective COX-2 inhibitors – Can reduce diuretic, natriuretic of diuretic and may lead to increased risk of kidney impairment and reduced antihypertensive effect
- Antidiabetic drugs – Dosage adjustment of antidiabetic may be required.
- Cholestyramine and colestipol – Reduced absorption of thiazides
- Lithium – Increases in serum lithium concentrations and lithium toxicity
- Carbamazepine – Increased risk of hyponatremia
Who makes irbesartan/hydrochlorothiazide?
Various FDA-approved generic manufacturers
Is irbesartan/hydrochlorothiazide safe in pregnancy?
irbesartan/hydrochlorothiazide may cause harm to your unborn baby and should be discontinued as soon as possible if you become pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription drug costs
How can NowPatient help me to lower the cost of my irbesartan/hydrochlorothiazide prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your irbesartan/hydrochlorothiazide prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient irbesartan/hydrochlorothiazide savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient irbesartan/hydrochlorothiazide savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for irbesartan/hydrochlorothiazide | Canadian Prescription Savings* for irbesartan/hydrochlorothiazide | irbesartan/hydrochlorothiazide Drug Coupon* | irbesartan/hydrochlorothiazide Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of irbesartan/hydrochlorothiazide?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for irbesartan/hydrochlorothiazide | Canadian Prescription Savings* for irbesartan/hydrochlorothiazide | irbesartan/hydrochlorothiazide Drug Coupon* | irbesartan/hydrochlorothiazide Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the irbesartan/hydrochlorothiazide savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the irbesartan/hydrochlorothiazide drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for irbesartan/hydrochlorothiazide, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the irbesartan/hydrochlorothiazide prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, irbesartan/hydrochlorothiazide is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed irbesartan/hydrochlorothiazide for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the irbesartan/hydrochlorothiazide prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the irbesartan/hydrochlorothiazide prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for irbesartan/hydrochlorothiazide
If you are having trouble paying for your irbesartan/hydrochlorothiazide medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for irbesartan/hydrochlorothiazide you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- irbesartan/hydrochlorothiazide is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers irbesartan/hydrochlorothiazide
- If irbesartan/hydrochlorothiazide is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for irbesartan/hydrochlorothiazide
If you are having trouble paying for your irbesartan/hydrochlorothiazide medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for irbesartan/hydrochlorothiazide you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers irbesartan/hydrochlorothiazide
- If irbesartan/hydrochlorothiazide is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for irbesartan/hydrochlorothiazide
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your irbesartan/hydrochlorothiazide treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for irbesartan/hydrochlorothiazide you will need to meet the following criteria:
- You must be currently insured and have coverage for irbesartan/hydrochlorothiazide
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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