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Hydrocortisone is available as a 25 mg suppository and 2.5% cream.

Hydrocortisone is a rectal corticosteroid medication used to treat hemorrhoids and other inflammatory conditions in and around the rectum.

Hydrocortisone is a topical corticosteroid. It works by lowering the amount of inflammatory chemicals that cause redness, itching, and swelling. This helps to relieve symptoms of hemorrhoids and lower rectum inflammation.

Hydrocortisone suppositories are typically used 3 times a day while a thin layer of the cream is applied to the affected area(s) 3 to 4 times daily.

Hydrocortisone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Hydrocortisone include:

• Burning
• Itching
• Skin irritation
• Dry skin

Serious side effects are rare with Hydrocortisone. Contact your healthcare provider immediately if you experience any of the following.

• Withdrawal symptoms: Long-term fatigue, muscle weakness, poor appetite, weight loss, belly pain

• There are no major drug interactions listed for Hydrocortisone. However, you should always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Various FDA-approved generic manufacturers

It is not known if Hydrocortisone will harm your unborn baby. Animal studies, however, suggest that excessive use of steroids can cause harm to unborn babies. You should talk to your healthcare provider before taking this medication if you are pregnant.

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