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Glycopyrrolate/Formoterol Fumarate is available as a metered dose inhaler containing a combination of glycopyrrolate (9 mcg) and formoterol fumarate (4.8 mcg) per inhalation.

Glycopyrrolate/Formoterol Fumarate is a LAMA / LABA combo that is used for the maintenance treatment of COPD.

Glycopyrrolate/Formoterol Fumarate is a combination inhaler. It contains two medications that work together to help treat COPD symptoms:

• Glycopyrrolate is a long-acting muscarinic antagonist (LAMA). It’s a type of anticholinergic medication that act on receptors in the lungs to improve your breathing
• Formoterol is a long-acting beta agonist (LABA). It relaxes and opens up the airways in your lungs to help you breathe easier

The typical dose of Glycopyrrolate/Formoterol Fumarate is 2 puffs inhaled through the mouth twice per day in the morning and evening.

Glycopyrrolate/Formoterol Fumarate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Use of a LABA, including formoterol fumarate, one of the activ e ingredients inglycopyrrolate/formoterol fumarate, without an inhaled corticosteroid is contraindicated in patients with asthma. Hypersensitivity to glycopyrrolate, formoterol fumarate, or to any component of this product

Common side effects of Glycopyrrolate/Formoterol Fumarate:

• Cough
• Urinary tract infection
• Chest pain
• Headache
• Dizziness
• Dry mouth

Serious side effects are rare with Glycopyrrolate/Formoterol Fumarate. Contact your healthcare provider immediately if you experience any of the following.

• Serious allergic reaction: hives, swelling of your face, lips, or tongue, difficulty breathing
• Sudden narrowing of your airways: difficulty breathing, wheezing, chest pain or tightness, cough
• Heart problems: dizziness, fatigue, tremor, nausea, rapid heartbeat, weakness, or difficulty sleeping

The following medications may interact with Glycopyrrolate/Formoterol Fumarate:

• Other adrenergic drugs may potentiate effect: Use with caution
• Xanthine derivatives, steroids, diuretics or non-potassium sparing diuretics may potentiaten hypokalemia or ECG changes. Use with caution
• Diuretics: Use with caution. Electrocardiographic changes and/or hypokalemia associated with non-potassium sparing diuretics may worsen with concomitant beta2-agonists
• Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution.
• May potentiate effect of formoterol fumarate on cardiovascular system
• Beta-blockers: Use with caution and only when medically necessary
• Anticholinergics: May interact additively with concomitantly used anticholinergicnmedications. Avoid administrations of Glycopyrrolate/Formoterol Fumarate with other anticholinergiccontaining drugs

Various FDA-approved generic manufacturers

It is not known if Glycopyrrolate/Formoterol Fumarate can harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking Glycopyrrolate/Formoterol Fumarate. You and your healthcare provider will decide if you should take Glycopyrrolate/Formoterol Fumarate while you are pregnant.

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