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Glipizide

GlipizidePrices, Coupons & Savings

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Looking for ways to save up to 90%* on your FDA-approved branded and generic medications?
You could enjoy savings using Now Patient’s mail-order online pharmacy or the Now Patient Rx Advantage Card at over 65,000 pharmacies.
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AVAILABLE CURRENTLY, ONLY IN
United States
*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Glipizide
    Generic for Glucotrol
    Rx
    5mg
    30 tablets $4.2 USD
    Save $1.80
  3. Glipizide
    Generic for Glucotrol
    Rx
    10mg
    30 tablets $4.5 USD
    Save $1.50
  4. Glipizide Extended Release (ER)
    Generic for Glucotrol XL
    Rx
    2.5mg
    30 extended release tablets $6.3 USD
    Save $6.60
  5. Glipizide Extended Release (ER)
    Generic for Glucotrol XL
    Rx
    5mg
    15 extended release tablets $5.1 USD
    Save $1.35
  6. Glipizide Extended Release (ER)
    Generic for Glucotrol XL
    Rx
    10mg
    30 extended release tablets $7.5 USD
    Save $5.40
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Do you need a prescription for glipizide?

Yes, glipizide is only available with a valid physician Rx.

How much is glipizide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase glipizide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for glipizide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a glipizide savings card?

Yes. Save up to 90% on your glipizide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a glipizide coupon provider in the US?

No. Now Patient does not provide glipizide coupons or FREE glipizide samples.

Do you accept commercial, Medicare or Medicaid coverage for glipizide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much glipizide?

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Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using glipizide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much glipizide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is glipizide?

Glipizide is an oral medication used in the management of type 2 diabetes mellitus. It belongs to a class of drugs known as sulfonylureas, which work by stimulating the release of insulin from the pancreas and increasing the body’s sensitivity to insulin.

FDA approval of glipizide

Glipizide is approved by the U.S. Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

Active ingredient of glipizide

The active ingredient of glipizide is glipizide.

US brand name of glipizide and manufacturer

Glipizide is available in the United States under various brand names, including Glucotrol and Glucotrol XL. It is manufactured by several pharmaceutical companies, including Pfizer, Inc.

UK brand name of glipizide and manufacturer

In the United Kingdom, glipizide is marketed under the brand name Minodiab. The manufacturer of Minodiab in the UK may vary.

Generic availability of glipizide

Generic versions of glipizide are available and are typically sold under the name glipizide followed by the name of the manufacturer.

Prescription requirement for glipizide

Glipizide is a prescription medication in the United States and the United Kingdom. It is important to consult a healthcare provider to determine if glipizide is appropriate for you and to receive the correct dosage instructions.

Availability of glipizide in the UK with NHS prescription

Glipizide is available with a National Health Service (NHS) prescription in the United Kingdom. It can be obtained from pharmacies with a valid prescription from a healthcare professional.

Conditions treated by glipizide

Glipizide is primarily used for the management of type 2 diabetes mellitus, particularly when diet and exercise alone are not sufficient to control blood sugar levels. It is important to note that glipizide is not used to treat type 1 diabetes, a condition in which the body does not produce any insulin.

How does glipizide work?

Glipizide works by stimulating the release of insulin from the beta cells in the pancreas and increasing the body’s sensitivity to insulin. This helps to lower blood sugar levels and improve glycemic control in individuals with type 2 diabetes. Insulin is a hormone that helps regulate blood sugar levels by facilitating the uptake of glucose (sugar) from the bloodstream into the cells of the body, where it can be used for energy. In people with type 2 diabetes, either the body does not produce enough insulin or the cells become resistant to its effects, leading to high blood sugar levels. When glipizide is taken, it binds to certain receptors on the beta cells of the pancreas. This binding triggers the release of insulin, which helps to lower blood sugar levels. Glipizide also helps to decrease the production of glucose by the liver, further reducing blood sugar levels. It is important to note that glipizide is typically used alongside a healthy diet and regular exercise to effectively manage diabetes. It is not a cure for diabetes, but rather a tool to help control blood glucose levels and prevent complications.

Forms of glipizide available

Glipizide is available as an immediate-release tablet and an extended-release tablet (Glucotrol XL) for once-daily dosing.

Dosage of glipizide

The dosage of glipizide may vary depending on individual factors, such as the severity of diabetes, response to treatment, and other medications being taken. It is important to follow the dosage instructions provided by the healthcare provider and not exceed the prescribed dose. Missing a dose of glipizide should be avoided, but if it happens, it is generally recommended to take the missed dose as soon as you remember, unless it is close to the time for the next dose. In that case, it is best to skip the missed dose and resume the regular dosing schedule. Taking extra doses of glipizide can increase the risk of low blood sugar.

Directions for glipizide use

Glipizide is typically taken orally with breakfast or the first main meal of the day. It is important to take glipizide exactly as prescribed by the healthcare provider and follow their instructions regarding the dosing schedule and any specific precautions. Store at room temperature away from moisture, heat, and light.

Side effects of glipizide

While glipizide is generally well-tolerated, there are potential side effects that individuals should be aware of.

  • The most common side effect of glipizide is low blood sugar, also known as hypoglycemia. Taking too much glipizide, not eating enough, or engaging in excessive physical activity can all contribute to this condition. Symptoms of low blood sugar include shakiness, drowsiness, blurred vision and weakness. It is important to monitor blood sugar levels regularly and be aware of the signs of low blood sugar while taking glipizide
  • Some individuals may experience weight gain while taking glipizide. This can be attributed to the medication’s effect on stimulating the production of insulin, which can lead to increased appetite and cravings for carbohydrates. It is important to maintain a healthy diet and engage in regular physical activity to help manage weight while on glipizide
  • Glipizide can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, constipation and stomach pain. These symptoms are usually mild and temporary but should be reported to a healthcare provider if they persist or worsen. It is important to stay hydrated and eat small, frequent meals to help alleviate digestive issues while taking glipizide
  • Rarely, glipizide can cause allergic reactions such as rash, itching, hives and trouble breathing. These symptoms should be reported to a healthcare provider immediately
  • In rare cases, glipizide can cause liver problems. Symptoms of liver disease/problems include yellowing of the skin or eyes, dark urine, abdominal pain, and fatigue. If any of these symptoms occur, it is important to seek medical attention

Warnings and precautions

  • People who have an enzyme deficiency known as glucose-6-phosphate dehydrogenase (G6PD) deficiency may develop hemolytic anemia with glipizide oral tablets. Be sure to talk with your doctor if you have this enzyme deficiency
  • People with type 1 diabetes or with diabetic ketoacidosis (DKA) should not take glipizide

Drug interactions 

Drug interactions may change how medications work or increase the risk of serious side effects. Here are some medications that should not be taken with glipizide:

  • Glipizide can enhance the blood sugar-lowering effect of beta-blockers, which are commonly used to treat conditions like high blood pressure and heart disease. This combination can increase the risk of hypoglycemia (low blood sugar). It is crucial to monitor blood sugar levels closely and consult with your healthcare provider if you are taking both medications
  • Glipizide belongs to the sulfonylurea class of drugs, taking it with other medications from the same class can increase the risk of hypoglycemia. Combining multiple sulfonylureas can lead to excessive lowering of blood sugar levels, which can be dangerous. This includes drugs like chlorpropamide, glibenclamide, and glimepiride
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aspirin can reduce the blood sugar-lowering effect of glipizide. They may also increase the risk of kidney disease when taken together. If you need to take NSAIDs for pain relief or other reasons, it is advisable to consult with your healthcare provider to determine the best course of action and to monitor your blood sugar levels closely
  • Glipizide can increase the blood sugar-lowering effect of thiazide diuretics, which are used to treat high blood pressure and fluid retention. This combination can increase the risk of hypoglycemia. It is important to monitor your blood sugar levels regularly and inform your healthcare provider if you are taking both medications
  • Glipizide can enhance the blood sugar-lowering effect of MAOIs (monoamine oxidase inhibitors) which are used to treat depression and anxiety. This can increase the risk of hypoglycemia. It is crucial to monitor your blood sugar levels closely and inform your healthcare provider if you are taking both medications
  • Glipizide may interact with anticoagulant medications like warfarin, increasing the risk of bleeding. It is important to closely monitor your blood clotting time and inform your healthcare provider if you are taking both medications

It is essential to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can evaluate the potential interactions and adjust your treatment plan accordingly to ensure the safe and effective use of glipizide. Remember to consult with your healthcare provider for medical advice while taking glipizide.

Is glipizide safe to take if I am pregnant or planning on becoming pregnant?

Glipizide is not recommended for use during pregnancy. It is important to discuss with your healthcare provider the use of glipizide if you are pregnant or planning to become pregnant. Alternative treatment options may be considered.

Is glipizide safe to take if I am breastfeeding?

Glipizide is not recommended for use while breastfeeding. It is important to consult with a healthcare provider for individualized recommendations.

Sources

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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