GAZYVA
Used for Cancer
Are you tired of high medication costs? Our service offers unbeatable savings on your GAZYVA prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by Genentech, Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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GAZYVA key facts
What is GAZYVA?
GAZYVA is the brand name for obinutuzumab IV infusion.
What dosages is GAZYVA available in?
GAZYVA is available as a 1,000 mg/40 mL (25 mg/mL) single-dose vial.
What is GAZYVA used for?
GAZYVA is a monoclonal antibody that is used to treat:
- Chronic lymphocytic leukemia (CLL)
- Follicular lymphoma (FL)
How does GAZYVA work?
GAZYVA is a monoclonal antibody that attaches to specific proteins called CD20 on B cells. B cells are a type of white blood cell. They are a part of your immune system and help your body make antibodies. Cancer cells usually have more CD20 proteins than normal, healthy cells. When GAZYVA attaches to CD20, an immune response gets triggered. Signals get sent out to attack and kill the cells that the medication is attached to. GAZYVA can also signal the cancer cells to die directly.
How do I take GAZYVA?
This medication is an injection into a vein (intravenously or IV) that’s given by a healthcare provider. The typical dose is 1,000 mg per infusion. GAZYVA is given weekly for the first 3 weeks in your first cycle. Then, it’s given every 3 to 4 weeks for future cycles, depending on your treatment regimen. Due to the risk for infusion reactions, your very first infusion will be split over 2 days, with 100 mg on the first day, then 900 mg on the second day.
Is it safe for me to take GAZYVA?
GAZYVA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. GAZYVA is contraindicated in patients with known hypersensitivity reactions (e.g., anaphylaxis) to obinutuzumab or any of the excipients, including serum sickness with prior obinutuzumab use.
GAZYVA Common Side Effects
Common side effects of GAZYVA:
- Infusion-related reactions
- Infections of the nose, throat, or lungs
- Cough
- Muscle, bone, or joint pain
- Fever
GAZYVA Serious Side Effects
Serious side effects are rare with GAZYVA. Contact your healthcare provider immediately if you experience any of the following.
- Serious infusion-related or allergic reactions: throat tightness, trouble breathing, itching or hives, swelling, chest pain, fast heartbeat, dizziness, flushing, chills, fever
- Infections (general): repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful urination, urinating more often than usual
- Brain infection: changes in mood or behavior, difficulty concentrating, vision loss, weakness, facial drooping, issues with balance or walking
- Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
Effects of other drugs, drug classes and over-the-counter products on GAZYVA
- There are no major drug interactions listed for GAZYVA. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes GAZYVA?
Genentech, Inc.
Is GAZYVA safe in pregnancy?
Based on its mechanism of action and findings in animals, GAZYVA can cause B-cell depletion in infants exposed to obinutuzumab. Females of reproductive potential to use effective contraception while receiving GAZYVA and for 6 months after the last dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my GAZYVA prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your GAZYVA prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient GAZYVA savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient GAZYVA savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for GAZYVA | Canadian Prescription Savings* for GAZYVA | GAZYVA Drug Coupon* | GAZYVA Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of GAZYVA?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for GAZYVA | Canadian Prescription Savings* for GAZYVA | GAZYVA Drug Coupon* | GAZYVA Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the GAZYVA savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the GAZYVA drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for GAZYVA, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the GAZYVA prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, GAZYVA is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed GAZYVA for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the GAZYVA prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the GAZYVA prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for GAZYVA
If you are having trouble paying for your GAZYVA medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for GAZYVA you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- GAZYVA is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers GAZYVA
- If GAZYVA is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for GAZYVA
If you are having trouble paying for your GAZYVA medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for GAZYVA you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers GAZYVA
- If GAZYVA is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for GAZYVA
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your GAZYVA treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for GAZYVA you will need to meet the following criteria:
- You must be currently insured and have coverage for GAZYVA
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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