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Fesoterodine is available as a 4 mg and 8 mg extended-release oral tablet.

Fesoterodine is an anticholinergic that is used to treat:
Overactive bladder (OAB) in adults Neurogenic detrusor overactivity (NDO) in children ages 6 years and older – brand Fesoterodine only

Fesoterodine is an anticholinergic medication that blocks acetylcholine. This is a chemical in the body that affects different bodily functions, including telling the bladder muscles to tighten so you can urinate. By blocking acetylcholine, Fesoterodine relaxes the bladder muscles so you have better control over urination.

Fesoterodine is dosed as follows: Overactive bladder (adults): The typical starting dose is 4 mg by mouth once a day. Your provider might raise your dose to 8 mg once a day depending on how you respond to the medication. Neurogenic detrusor overactivity (children ages 6 years and older, weighing at least 25 kg): The typical dose is 4 mg by mouth once a day. If needed, your child’s provider might raise their dose to 8 mg once a day depending on how your child responds to the medication. Your dose might differ if you have kidney problems or if you’re taking certain medications that interact with Fesoterodine.

Fesoterodine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:
Known or suspected hypersensitivity to Fesoterodine or any of its ingredients or to tolterodine tartrate tablets or tolterodine tartrate extended-release capsules.

• Urinary retention
• Gastric retention
• Uncontrolled narrow-angle glaucoma

Common side effects of Fesoterodine:

• Dry mouth
• Constipation
• Urinary tract infection
• Upper respiratory tract infection
• Dry eyes

Serious side effects are rare with Fesoterodine. Contact your healthcare provider immediately if you experience any of the following.

• Angioedema (severe swelling): swelling of the face, arms or legs, lips, tongue, or throat

The following medications may interact with Fesoterodine:

• Antimuscarinic Drugs: Coadministration of Fesoterodine with other antimuscarinic agents that produce dry mouth, constipation, urinary retention, and other anticholinergic pharmacological effects may increase the frequency and/or severity of such effects
• CYP3A4 Inhibitors: Doses of Fesoterodine greater than 4 mg are not recommended in adult patients taking strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, and clarithromycin

Various FDA-approved generic manufacturers

There are no adequate and well-controlled studies in pregnant women. Fesoterodine should be used during pregnancy only if clearly needed.

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