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Doxazosin

Doxazosin Generic

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AVAILABLE CURRENTLY, ONLY IN
United States
*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Doxazosin Mesylate
    Generic for Cardura
    Rx
    4mg
    30 tablets $5.7 USD
    Save $14.10
  3. Doxazosin Mesylate
    Generic for Cardura
    Rx
    2mg
    30 tablets $6.3 USD
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  4. Doxazosin Mesylate
    Generic for Cardura
    Rx
    8mg
    30 tablets $6.9 USD
    Save $12.90
  5. Doxazosin Mesylate
    Generic for Cardura
    Rx
    1mg
    30 tablets $6 USD
    Save $13.80
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Do you need a prescription for doxazosin?

Yes, doxazosin is only available with a valid physician Rx.

How much is doxazosin without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase doxazosin, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for doxazosin in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a doxazosin savings card?

Yes. Save up to 90% on your doxazosin with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a doxazosin coupon provider in the US?

No. Now Patient does not provide doxazosin coupons or FREE doxazosin samples.

Do you accept commercial, Medicare or Medicaid coverage for doxazosin in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much doxazosin?

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Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using doxazosin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much doxazosin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic doxazosin?

Generic doxazosin refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of doxazosin

Doxazosin is approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension (high blood pressure) and benign prostatic hyperplasia (BPH).

Active ingredient of doxazosin

The active ingredient of doxazosin is doxazosin mesylate.

US brand name of doxazosin and manufacturer

Doxazosin is available in the US under the brand name Cardura. The manufacturer may vary depending on the brand name.

UK brand name of doxazosin and manufacturer

In the UK, doxazosin is available under various brand names, including Cardura. The manufacturer may vary depending on the brand name.

Prescription requirement for doxazosin

A prescription (Rx) is required for doxazosin in both the US and the UK.

Availability of doxazosin in the UK with NHS prescription

Doxazosin is available in the UK with an NHS prescription.

Conditions treated by doxazosin

Doxazosin is commonly used as an antihypertensive medication to lower blood pressure in patients with hypertension. It works by relaxing the blood vessels, allowing for easier blood flow and reducing the workload on the heart.

Another common use for doxazosin is in the management of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland that can cause urinary symptoms. Doxazosin helps relax the muscles in both the prostate gland and bladder neck, relieving symptoms such as frequent urination and difficulty starting or maintaining urination.

Please note that off-label uses should be discussed with healthcare professionals before considering their usage.

How does doxazosin work?

Doxazosin belongs to a class of drugs called alpha-blockers and is specifically an alpha-1 adrenergic antagonist. It works by blocking the alpha-1 receptors located in smooth muscle cells of the arteries and prostate gland. By doing so, it relaxes these muscles, leading to dilation of blood vessels and improved urine flow in patients with benign prostatic hyperplasia (BPH).

When administered orally, doxazosin is rapidly absorbed from the gastrointestinal tract. It undergoes extensive hepatic metabolism via cytochrome P450 enzymes before being eliminated primarily through fecal excretion. The drug reaches peak plasma concentrations within 2 to 3 hours after administration.

As an antihypertensive agent, doxazosin effectively lowers blood pressure by dilating both arterial and venous blood vessels throughout the body. This relaxation reduces peripheral resistance and results in decreased systemic vascular resistance without a significant impact on heart rate or cardiac output. Consequently, it helps manage hypertension while improving overall cardiovascular health.

Forms of doxazosin available

Doxazosin comes as a tablet and an extended-release tablet to take by mouth.

Dosage of doxazosin

The dosage of doxazosin may vary depending on the individual’s specific condition, response to treatment, and other factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Directions for doxazosin use

Doxazosin should be taken exactly as directed by the healthcare provider. The tablets are usually taken orally, with or without food. It is important to take doxazosin consistently and at the same time each day for the best results.

Store at room temperature away from moisture, heat and from the reach of children.

Warnings and precautions for doxazosin

  • Doxazosin may have certain risks and potential side effects. Discussing these with a healthcare provider before starting the medication is important
  • Doxazosin may cause dizziness or fainting, especially when standing up from a sitting or lying position. It is important to get up slowly and avoid sudden position changes
  • It is important to inform a healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can evaluate the potential adverse effects and make necessary adjustments to your treatment plan to ensure the safety and effectiveness of the medications
  • Get emergency medical advice and help if you have signs of an allergic reaction to doxazosin: hives, trouble breathing, swelling of your face, lips, tongue, or throat

Drug interactions for doxazosin

  • When prescribing doxazosin in combination with other antihypertensive medications, exercise caution as the combined effects may lead to excessive hypotension. Monitor blood pressure closely and adjust the dosage accordingly to ensure optimal control
  • Some notable examples include nonsteroidal anti-inflammatory drugs (NSAIDs) and phosphodiesterase type 5 inhibitors for erectile dysfunction (e.g. sildenafil, tadalafil and vardenafil), which may increase the risk of adverse effects such as dizziness or fainting. Precautions should be taken when co-administering these drugs
  • Taking multiple alpha-blockers simultaneously can increase the risk of side effects such as dizziness or low blood pressure. Carefully evaluate each patient’s medical history before considering this combination, and closely monitor for any signs of adverse reactions during treatment

Use of doxazosin if pregnant or planning pregnancy

The use of doxazosin during pregnancy and breastfeeding should be discussed with a healthcare provider. It is generally not recommended for use during pregnancy unless the potential benefits outweigh the risks.

Possible side effects of doxazosin

Common side effects of doxazosin may include lightheadedness, drowsiness, headache, and low blood pressure. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to doxazosin

Other alpha-1 blockers, such as terazosin and tamsulosin, may be used as alternatives for the treatment of hypertension and BPH.

Sources

Disclaimer

Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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