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darolutamide

darolutamide

Used for Cancer

View darolutamide savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or darolutamide Patient Assistance Program.

Programs are suitable for individuals who want to buy darolutamide without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

Learn more about darolutamide

What dosages is darolutamide available in?

What dosages is darolutamide available in?

darolutamide is available as a 300 mg oral tablet.

What is darolutamide used for?

What is darolutamide used for?

darolutamide is an anti-androgen and is used for the following:
Castration-resistant prostate cancer that hasn’t yet spread to other areas of the body Metastatic, hormone-sensitive prostate cancer, given together with a chemotherapy called docetaxel (Taxotere)

How does darolutamide work?

How does darolutamide work?

darolutamide is an androgen receptor inhibitor (antiandrogen). It’s a type of hormone therapy that works by blocking testosterone from binding to prostate cancer cells. Without testosterone, cancer cells won’t have the fuel they need to grow or spread as well.

How do I take darolutamide?

How do I take darolutamide?

darolutamide is dosed as follows:

  • Adults: The typical dose is 600 mg taken by mouth twice a day

Your dose might be different if you have kidney or liver problems.

Is it safe for me to take darolutamide?

Is it safe for me to take darolutamide?

darolutamide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

darolutamide Common Side Effects

darolutamide Common Side Effects

Common side effects of darolutamide:

  • Extreme tiredness
  • Lower red blood cell count
  • Higher blood sugar levels
  • Lower white blood cell count
  • Changes in liver labs
  • Lower blood calcium level
  • Constipation
  • Not eating as much or not feeling hungry
  • Rash
  • Bleeding that’s difficult to stop
  • Weight gain
  • Headaches, dizziness, and other symptoms of high blood pressure
darolutamide Serious Side Effects

darolutamide Serious Side Effects

Serious side effects are rare with darolutamide. Contact your healthcare provider immediately if you experience any of the following.

  • Seizures
  • Heart problems: chest pain, racing heartbeat, shortness of breath, arm or shoulder pain, swelling of your legs or feet, sudden weight gain, sweating, fatigue, dizziness, nausea or vomiting
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
  • Severe skin reactions: painful blisters, skin wounds, peeling skin
Effects of other drugs, drug classes and over-the-counter products on darolutamide

Effects of other drugs, drug classes and over-the-counter products on darolutamide

The following medications may interact with darolutamide:

  • Combined P-gp and Strong or Moderate CYP3A Inducers: Avoid concomitant use
  • Combined P-gp and Strong CYP3A Inhibitors: Monitor patients more frequently for darolutamide adverse reactions
  • BCRP Substrates: Avoid concomitant use with drugs that are BCRP substrates where possible. If used together, monitor patients more frequently for adverse reactions and consider dose reduction of the BCRP substrate drug
  • OATP1B1 and OATP1B3 Substrates: Concomitant use of darolutamide may increase the plasma concentrations of OATP1B1 or OATP1B3 substrates. If used together, monitor patients more frequently for adverse reactions and consider dose reduction of these drugs
Who makes darolutamide?

Who makes darolutamide?

Various FDA-approved generic manufacturers

Is darolutamide safe in pregnancy?

Is darolutamide safe in pregnancy?

darolutamide can cause harm to your unborn baby and loss of pregnancy (miscarriage). Males who have female partners who may become pregnant should use effective birth control (contraception) during treatment and for 1 week after the last dose of darolutamide. Talk with your healthcare provider about birth control methods.

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What to do if you missed your darolutamide dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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