Your provider will help determine your dose of Creon based on different factors such as your symptoms, your weight, and the fat content of your meals The dose of Creon is based on units of the digestive enzymes. The typical dosing range is 500 lipase units/kg of body weight to 2,500 lipase units/kg of body weight by mouth with each meal. Your provider might ask you to take a smaller dose of Creon when you eat snacks in between meals The maximum total daily dose is less than or equal to 10,000 lipase units/kg of body weight. The daily dose assumes you eat 3 meals per day and have 2 to 3 snacks per day

Save up to 90% on Creon with Coupons, Discount Cards & Patient Assistance Programs

Compare drug coupons, Rx discount cards, Canadian pharmacy savings, telehealth visits, and patient assistance programs side by side. Find what you could pay with or without insurance and choose the option that works for you.

Manufactured by AbbVie Inc.

Creon (Pancrelipase) medication packaging - save with coupons and discount programs

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Creon Prices and Programs Compared

You can lower the cost of your Creon Rx by using one of the 4 drug savings programs below.

Lowest price today

Drug Coupon

For people with commercial or employer insurance.

$50.00

Your copay under Abbott Patient Assistance, with commercial insurance

The drug maker covers part of your copay. Bring the card to the pharmacy with your insurance and pay the reduced amount.

Check eligibility

Not available on Medicare, Medicaid, TRICARE or VA plans. Annual limits apply.

Canadian Pharmacy

Anyone can use this. No insurance needed.

Choose your supply

$53.00for 100 delayed release capsules

$0.53 each, shipped to your door

Dispensed by our licensed partner pharmacy in Canada and posted direct to you. Valid US prescription required.

Sold in Canada under the brand name Creon. Same active ingredient and strength as your US prescription.

Typically 10 to 14 days by post. Ref 44820-61.Price updated on 09/14/26

Rx Advantage Card

Free to use. Works with or without insurance.

$1,154.15

Creon 36000-114000unit at Sentara To Home Sch

Virginia Oncology Associates$1,154.15
Amazon Pharmacy #021$1,154.40

5 more pharmacies nearby

Show the card at the counter and pay the price above. Nothing to sign up for, and it never expires.

Get my free card

Prices refresh Monthly and are held at the pharmacy for 1 month.Price updated on 08/01/26Prices are generated from the zipcode 23666.

Patient Assistance Program

For uninsured and underinsured people under the income limit.

Medication supplied free by the manufacturer

Answer six questions and we will tell you in under a minute whether you are inside the income limit, then help you file the form.

Check eligibility

Approval usually takes 2 to 4 weeks. Your prescriber signs one section.

Programs not available for Creon at the moment

TrumpRx Savings

For cash paying, uninsured and commercially insured people.

Not available

Some drugs are cheaper direct from the maker, and some are cheaper as a US generic. We show you both so you can pick.

Not open to Medicare, Medicaid, TRICARE or VA patients. NowPatient is not affiliated with TrumpRx.gov.

Telehealth Visit

Open to everyone. No insurance needed.

Not available

Speak to a US licensed clinician by video, usually the same day. If they prescribe, we send it to the pharmacy you pick.

You only pay if the appointment goes ahead. No membership.

Related generics

Pancrelipase

View Savings

Key facts about Creon

What is Creon?

Creon is the brand name for pancrelipase and is available as an delayed-release oral capsule.

What dosages is Creon available in?

Creon is available as a delayed-release oral capsule that contains:

3,000 USP units of lipase; 9,500 USP units of protease; and 15,000 USP units of amylase or 6,000 USP units of lipase; 19,000 USP units of protease; and 30,000 USP units of amylase or 12,000 USP units of lipase; 38,000 USP units of protease; and 60,000 USP units of amylase or
24,000 USP units of lipase; 76,000 USP units of protease; and 120,000 USP units of amylase or 36,000 USP units of lipase; 114,000 USP units of protease; and 180,000 USP units of amylase.

What is Creon used for?

Creon is an enzyme and is used to treat pancreatic insufficiency (not enough digestive enzymes)

How does Creon work?

Creon replaces three important digestive or pancreatic enzymes (lipase, amylase, and protease) that are normally made in the pancreas and help to break down food.

How do I take Creon?

Your provider will help determine your dose of Creon based on different factors such as your symptoms, your weight, and the fat content of your meals
The dose of Creon is based on units of the digestive enzymes. The typical dosing range is 500 lipase units/kg of body weight to 2,500 lipase units/kg of body weight by mouth with each meal. Your provider might ask you to take a smaller dose of Creon when you eat snacks in between meals
The maximum total daily dose is less than or equal to 10,000 lipase units/kg of body weight. The daily dose assumes you eat 3 meals per day and have 2 to 3 snacks per day

Is it safe for me to take Creon?

Creon is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Creon Common Side Effects

Common side effects of Creon:

Vomiting
Dizziness
Cough
Changes in your blood sugar (it can go up or down)
Stomach pain
Passing gas
Changes in your stool or bowel movement

Creon Serious Side Effects

Serious side effects are rare with Creon. Contact your healthcare provider immediately if you experience any of the following.

Severe allergic reaction: feeling lightheaded, confused, trouble breathing, skin rash, swollen lips, nausea, vomiting

Effects of other drugs, drug classes and over-the-counter products on Creon

There are no major drug interactions listed for Creon. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Who makes Creon?

AbbVie Inc.

Is Creon safe in pregnancy?

It is not known if Creon will harm your unborn baby. If you become pregnant while receiving Creon, talk to your healthcare provider.

What is the generic name for Creon?

Pancrelipase

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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