View CREON savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or CREON Patient Assistance Program.

Programs are suitable for individuals who want to buy CREON without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by AbbVie Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Save up to 90%

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    Canadian Prescription Savings

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  • Available

    Drug Coupons

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    Patient Assistance Programs

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about CREON

What is CREON?

What is CREON?

CREON is the brand name for pancrelipase and is available as an delayed-release oral capsule.

What dosages is CREON available in?

What dosages is CREON available in?

CREON is available as a delayed-release oral capsule that contains:

3,000 USP units of lipase; 9,500 USP units of protease; and 15,000 USP units of amylase or 6,000 USP units of lipase; 19,000 USP units of protease; and 30,000 USP units of amylase or 12,000 USP units of lipase; 38,000 USP units of protease; and 60,000 USP units of amylase or
24,000 USP units of lipase; 76,000 USP units of protease; and 120,000 USP units of amylase or 36,000 USP units of lipase; 114,000 USP units of protease; and 180,000 USP units of amylase.

What is CREON used for?

What is CREON used for?

  • CREON is an enzyme and is used to treat pancreatic insufficiency (not enough digestive enzymes)
How does CREON work?

How does CREON work?

CREON replaces three important digestive or pancreatic enzymes (lipase, amylase, and protease) that are normally made in the pancreas and help to break down food.

How do I take CREON?

How do I take CREON?

  • Your provider will help determine your dose of CREON based on different factors such as your symptoms, your weight, and the fat content of your meals
  • The dose of CREON is based on units of the digestive enzymes. The typical dosing range is 500 lipase units/kg of body weight to 2,500 lipase units/kg of body weight by mouth with each meal. Your provider might ask you to take a smaller dose of CREON when you eat snacks in between meals
  • The maximum total daily dose is less than or equal to 10,000 lipase units/kg of body weight. The daily dose assumes you eat 3 meals per day and have 2 to 3 snacks per day
Is it safe for me to take CREON?

Is it safe for me to take CREON?

CREON is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

CREON Common Side Effects

CREON Common Side Effects

Common side effects of CREON:

  • Vomiting
  • Dizziness
  • Cough
  • Changes in your blood sugar (it can go up or down)
  • Stomach pain
  • Passing gas
  • Changes in your stool or bowel movement
CREON Serious Side Effects

CREON Serious Side Effects

Serious side effects are rare with CREON. Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: feeling lightheaded, confused, trouble breathing, skin rash, swollen lips, nausea, vomiting
Effects of other drugs, drug classes and over-the-counter products on CREON

Effects of other drugs, drug classes and over-the-counter products on CREON

  • There are no major drug interactions listed for CREON. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes CREON?

Who makes CREON?

AbbVie Inc.

Is CREON safe in pregnancy?

Is CREON safe in pregnancy?

It is not known if CREON will harm your unborn baby. If you become pregnant while receiving CREON, talk to your healthcare provider.


What to do if you missed your CREON dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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