cinacalcet
Used for Chronic Kidney Disease
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Manufactured by various FDA-approved generic manufacturers.
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cinacalcet Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is cinacalcet available in?
cinacalcet is available as a 30 mg, 60 mg, and 90 mg oral tablet.
What is cinacalcet used for?
cinacalcet is a calcimimetic that is used to treat high calcium levels from:
- Overactive parathyroid that can’t be removed by surgery
- Overactive parathyroid in people with chronic kidney disease (CKD) who are on dialysis
- Parathyroid cancer
How does cinacalcet work?
cinacalcet is in a drug class called calcimimetics. It works on your parathyroid glands to lower the amount of parathyroid hormone they produce. In doing so, it lowers the amount of calcium and phosphorus in your body.
How do I take cinacalcet?
For overactive parathyroid in CKD: The typical starting dose is 30 mg by mouth once daily with food or after a meal. Your provider will adjust the dose based on your parathyroid hormone levels, as well as blood calcium and phosphorus levels. The maximum dose is 180 mg once daily. For overactive parathyroid and parathyroid cancer: The typical starting dose is 30 mg by mouth twice daily with food or after a meal. Your provider will adjust the dose based on your blood calcium levels. The maximum dose is 90 mg three to four times daily.
Is it safe for me to take cinacalcet?
cinacalcet is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if your serum calcium is less than
the lower limit of the normal range.
cinacalcet Common Side Effects
Common side effects of cinacalcet:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Muscle aches
- Dizziness
cinacalcet Serious Side Effects
Serious side effects are rare with cinacalcet. Contact your healthcare provider immediately if you experience any of the following.
- Very low levels of calcium: muscle pain and spasms, pins and needles sensation, seizures
- Stomach bleed: vomiting that won’t stop, blood in your vomit or stool, black, tarry stools, really bad stomach pain
- Heart problems: abnormal heartbeats, trouble breathing, sudden weight gain or swelling of your arms and legs, feeling confused
Effects of other drugs, drug classes and over-the-counter products on cinacalcet
The following medications may interact with cinacalcet:
- Co-administration with a strong CYP3A4 inhibitor may increase serum levels of cinacalcet. Dose adjustment and monitoring of iPTH serum phosphorus and serum calcium may be required
- Cinacalcet is a strong inhibitor of CYP2D6. Dose adjustments may be required for concomitant medications that are predominantly metabolized by CYP2D6
Who makes cinacalcet?
Various FDA-approved generic manufacturers
Is cinacalcet safe in pregnancy?
It is not known if cinacalcet will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
What to do if you missed your cinacalcet dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What are cinacalcet used for?
What foods should you avoid when taking cinacalcet?
Does parathyroid affect weight?
Who should not take cinacalcet?
What happens if hyperparathyroidism is left untreated?
When should cinacalcet be given?
Should you take vitamin D if you have hyperparathyroidism?
What does cinacalcet do to bone?
What are the side effects of taking cinacalcet?
What are the problems with cinacalcet?
Does cinacalcet improve bone density?
What happens if parathyroid hormone is high?
What happens when you stop taking cinacalcet?
Can you take vitamin D with cinacalcet?
Does cinacalcet cause weight gain?
How long can you live with hyperparathyroidism?
Does cinacalcet cause weight loss?
What effect does cinacalcet have on urine calcium?
Is cinacalcet hazardous?
Does cinacalcet affect blood pressure?
What is the mechanism of action for cinacalcet?
What does cinacalcet do to calcium?
What is the difference between calcitriol and cinacalcet?
Does cinacalcet affect vitamin D?
How long does it take for cinacalcet to lower calcium?
What is the difference between Sensipar and cinacalcet?
Why is cinacalcet used in CKD?
What does Sensipar do to calcium?
When should I stop taking cinacalcet before parathyroidectomy?
Why does cinacalcet cause hypocalcemia?
How long does it take for cinacalcet to work?
What is the role of cinacalcet in primary hyperparathyroidism?
What is the first line treatment for primary hyperparathyroidism?
What is the most effective treatment for primary hyperparathyroidism?
What medications should be avoided in primary hyperparathyroidism?
What are the side effects of cinacalcet?
Why is vitamin D used to treat hyperparathyroidism?
What happens to calcium levels in primary hyperparathyroidism?
Can cinacalcet cause weight gain?
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