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chlorthalidone Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is chlorthalidone available in?

What dosages is chlorthalidone available in?

chlorthalidone is available as a 25 mg and 50 mg oral tablet.

What is chlorthalidone used for?

What is chlorthalidone used for?

chlorthalidone is a diuretic (water pill) and is used to treat hypertension (high blood pressure), and swelling from fluids (edema) caused by heart failure, kidney problems, liver problems, or corticosteroid and estrogen therapy.

How does chlorthalidone work?

How does chlorthalidone work?

chlorthalidone is a thiazide-like diuretic (water pill) that makes you urinate more. It works in the kidneys to remove extra water and certain electrolytes, while lowering blood pressure and getting rid of swelling.

How do I take chlorthalidone?

How do I take chlorthalidone?

chlorthalidone is typically dosed as 25 mg by mouth once daily for hypertension. If needed, your physician will adjust your dose. The maximum dose is 100 mg once daily. For swelling, the typical starting dose is 50 mg to 100 mg by mouth once daily. If needed, your provider will adjust your dose. The maximum dose is 200 mg once daily.

Is it safe for me to take chlorthalidone?

Is it safe for me to take chlorthalidone?

chlorthalidone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have anuria.

chlorthalidone Common Side Effects

chlorthalidone Common Side Effects

Common side effects of chlorthalidone include:

  • Urinating more
  • Dizziness
  • Headache
  • Sensitivity to the sun
chlorthalidone Serious Side Effects

chlorthalidone Serious Side Effects

Serious side effects are rare with chlorthalidone. Contact your healthcare provider immediately if you experience any of the following:

  • Allergic reaction (difficulty breathing, swelling of the tongue/mouth/throat, rash or hives).
  • Kidney problems (not urinating as often as you usually do, feeling tired, confusion).
  • Severe liver issues (yellowing of the eyes or skin, pale stool, dark urine, confusion).
  • Electrolyte levels out of balance (muscle weakness, muscle twitching, tiredness, confusion, seizures).
Effects of other drugs, drug classes and over-the-counter products on chlorthalidone

Effects of other drugs, drug classes and over-the-counter products on chlorthalidone

The following medications may interact with chlorthalidone:

  • Antihypertensive drugs – Chlorthalidone may add to or potentiate the action of other antihypertensive drugs
  • Lithium – Lithium renal clearance is reduced by chlorthalidone, increasing the risk of lithium toxicity
Who makes chlorthalidone?

Who makes chlorthalidone?

Various FDA-approved generic manufacturers

Is chlorthalidone safe in pregnancy?

Is chlorthalidone safe in pregnancy?

chlorthalidone may cause harm to your unborn baby and should not be used as first-line therapy to treat hypertension in pregnant women.


What to do if you missed your chlorthalidone dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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