Key facts about Cerezyme
What is Cerezyme?
Cerezyme is the brand name for imiglucerase IV infusion.
What dosages is Cerezyme available in?
Cerezyme is available as 400 units of imiglucerase in a singledose vial.
What is Cerezyme used for?
Cerezyme is a hydrolytic lysosomal glucocerebrosidase-specific enzyme that is used to treat type 1 Gaucher disease in adults and children 2 years of age or older.
How does Cerezyme work?
Cerezyme works as an enzyme replacement for glucocerebrosidase and helps your body break down glucosylceramide.
How do I take Cerezyme?
Cerezyme is an intravenous (IV) infusion that is administered by a healthcare provider. The dose depends on your weight and how severe your Type 1 Gaucher disease symptoms are. Your healthcare provider will determine the appropriate dose for you each time. In general, the dose ranges from 2.5 units/kg three times a week to 60 units/kg once every two weeks.
Is it safe for me to take Cerezyme?
Cerezyme is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Cerezyme Common Side Effects
Common side effects of Cerezyme:
- Itching
- Fever
- Rash
- Chills
- Chest discomfort
Cerezyme Serious Side Effects
Serious side effects are rare with Cerezyme. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic or infusion-related reactions: throat tightness, trouble breathing, cough, itching or hives, flushing, swelling, chest pain, skin turning blue, fast heartbeat, low blood pressure, dizziness, fainting
Effects of other drugs, drug classes and over-the-counter products on Cerezyme
- There are no major drug interactions listed for Cerezyme. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Cerezyme?
Genzyme Corporation
Is Cerezyme safe in pregnancy?
It is not known if Cerezyme will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking Cerezyme. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to
Cerezyme during pregnancy. Pregnant women exposed to Cerezyme and health care providers are encouraged to contact the Gaucher patient registry at 1-800-745-4447, extension 15500 or visit Registry Nxt
