Used for Cancer

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Manufactured by Eli Lilly & Company

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

ALIMTA Uses, Side Effects, Interactions, Warnings & Dosing

What is ALIMTA?

What is ALIMTA?

ALIMTA is the brand name for pemetrexed and is available as IV injection.

What dosages is ALIMTA available in?

What dosages is ALIMTA available in?

ALIMTA is available as a 100 mg or 500 mg IV injection.

What is ALIMTA used for?

What is ALIMTA used for?

ALIMTA is an antimetabolite and is used for the following:

  • Advanced or metastatic non-squamous non-small cell lung cancer (NSCLC)
  • Advanced or metastatic malignant mesothelioma
How does ALIMTA work?

How does ALIMTA work?

ALIMTA is a type of chemotherapy called an antimetabolite. It stops rapidly growing cells (like cancer cells) from producing the chemicals needed to build their genetic material and other substances important for cells to grow and divide.

How do I take ALIMTA?

How do I take ALIMTA?

  • Your treatment team will determine your ALIMTA dose based on your body surface area (BSA), which is calculated using your height and weight
  • The typical dose is 500 mg/m2 given as an infusion through the vein (IV) every 3 weeks by a healthcare provider
Is it safe for me to take ALIMTA?

Is it safe for me to take ALIMTA?

ALIMTA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ALIMTA Common Side Effects

ALIMTA Common Side Effects

Common side effects of ALIMTA:

  • Low blood cell counts
  • Higher blood sugar levels
  • Feeling very tired
  • Nausea
  • Signs of stress to the liver and kidney on blood tests
  • Constipation
  • Low blood electrolyte and protein levels
  • Diarrhea
ALIMTA Serious Side Effects

ALIMTA Serious Side Effects

Serious side effects are rare with ALIMTA. Contact your healthcare provider immediately if you experience any of the following.

  • Lower blood cell counts: unusual bleeding or bruising, fever, chills, body aches, tiredness
  • Serious kidney problems: feeling confused, tiredness, nausea, vomiting, itchy skin, making little to no urine
  • Severe skin problems: burning, redness, rashes, blisters, or peeling skin
  • Lung damage: cough, trouble catching your breath, fever
Effects of other drugs, drug classes and over-the-counter products on ALIMTA

Effects of other drugs, drug classes and over-the-counter products on ALIMTA

The following medications may interact with ALIMTA:

  • Ibuprofen increased risk of ALIMTA toxicity in patients with mild to moderate renal impairment. Modify the ibuprofen dosage as recommended for patients with a creatinine clearance between 45 mL/min and 79 mL/min
Who makes ALIMTA?

Who makes ALIMTA?

Eli Lilly & Company

Is ALIMTA safe in pregnancy?

Is ALIMTA safe in pregnancy?

Based on findings from animal studies and its mechanism of action, ALIMTA can cause fetal harm when administered to a pregnant woman. Women should use effective contraception during treatment with ALIMTA and for 6 months after the last dose. Males with female partners of reproductive potential to use effective contraception during treatment with ALIMTA and for 3 months after the last dose.


What to do if you missed your ALIMTA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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