alemtuzumab
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Manufactured by various FDA-approved generic manufacturers.
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alemtuzumab Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is alemtuzumab available in?
alemtuzumab is available as a 12 mg/1.2 mL (10 mg/mL) single-use vial.
What is alemtuzumab used for?
alemtuzumab is an anti-CD52 monoclonal antibody that is used to treat relapsing forms of multiple sclerosis (MS) in adults who haven’t responded well enough to at least two other MS medications.
How does alemtuzumab work?
alemtuzumab is a CD52 monoclonal antibody. The exact way it treats MS isn’t well-understood. But it’s thought to dampen the immune system by attaching to a protein called CD52 found on certain immune cells. This temporarily lowers the amount of immune cells in the body, which can lessen inflammation and bring relief of MS symptoms.
How do I take alemtuzumab?
A full treatment with alemtuzumab includes 2 treatment courses, given a year apart.
First treatment course: The typical dose is 12 mg infused into the veins (IV) once daily for 5 days by a healthcare provider.
Second treatment course: The second treatment course is given 1 year after the first treatment course. The typical dose is 12 mg infused IV once daily for 3 days by a healthcare provider.
If needed, your provider might have you continue with additional treatment courses of alemtuzumab. Each additional course can be given 1 year after your last course. The typical dose is 12 mg infused IV once daily for 3 days.
Is it safe for me to take alemtuzumab?
alemtuzumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have HIV.
alemtuzumab Common Side Effects
- Common side effects of alemtuzumab:
- Rash
- Headache
- Fever
- Sore throat, runny nose
- Nausea
- Urinary tract infection
- Tiredness
- Difficulty sleeping
- Upper respiratory tract infection
- Herpes viral infection
- Hives
alemtuzumab Serious Side Effects
Serious side effects are rare with alemtuzumab. Contact your healthcare provider immediately if you experience any of the following.
Autoimmune problems: see the risks and warnings section for more specific autoimmune problems and their associated signs and symptoms
Serious allergic and infusion reactions: low or high blood pressure, chest pain, low or high heart rate, headache, fever, rash, nausea, hives, difficulty sleeping, chills, flushing, fatigue, shortness of breath, dizziness
Stroke: sudden trouble speaking, droopy face, sudden confusion, numbness or weakness in the face, arm, or leg
Cancers: new lumps or swelling in your neck, pain in the front of the neck, changes in your voice, trouble swallowing or breathing, constant cough not due to an infection, changes in your skin
Inflammatory problems: see the risks and warnings section for more specific inflammatory problems and their associated signs and symptoms
Serious infections: fever, difficulty breathing, diarrhea, weakness, cough, stomach pain, sweating, chills, burning when you urinate, urinating more often
Effects of other drugs, drug classes and over-the-counter products on alemtuzumab
- There are no major drug interactions listed for alemtuzumab. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes alemtuzumab?
Various FDA-approved generic manufacturers
Is alemtuzumab safe in pregnancy?
alemtuzumab may harm your unborn
baby. You should use birth control while receiving alemtuzumab and for 4 months
after your course of treatment.
What to do if you missed your alemtuzumab dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Are the NowPatient alemtuzumab savings programs suitable for everyone, regardless of insurance status?
Are the NowPatient drug savings programs suitable for brand and generic versions of alemtuzumab?
If you have Medicare Part D or Medicare Advantage and none of the alemtuzumab savings options are applicable or affordable for me, what can you do?
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If I have federal, state or commercial insurance and none of the alemtuzumab prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
Why was alemtuzumab discontinued?
Is alemtuzumab available in the US?
How much does alemtuzumab cost?
Is alemtuzumab approved by the FDA?
What is the controversy with alemtuzumab?
What is the success rate of alemtuzumab?
What is the black box warning for alemtuzumab?
Is alemtuzumab cardiac toxicity?
What is the cost of alemtuzumab?
How long is the treatment for alemtuzumab?
What are the precautions for alemtuzumab?
Does alemtuzumab cause blurred vision?
Is alemtuzumab an Immunotherapy?
What premedication is given with alemtuzumab?
Is alemtuzumab immunosuppression?
What is the recommended usage of alemtuzumab for the treatment of MS?
What class of drug is alemtuzumab?
Is alemtuzumab a chemotherapy?
What are the side effects of alemtuzumab Campath?
How long does an infusion for MS take?
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When was alemtuzumab approved for MS?
What is the mechanism of action of alemtuzumab?
What class of drug is alemtuzumab?
How long is alemtuzumab infusion?
What is the function of alemtuzumab?
What is the target of alemtuzumab?
How does alemtuzumab work multiple sclerosis?
How does alemtuzumab work in aplastic anemia?
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