Question 1

How can I lower the cost of my Activase

Accepted Answer

You can lower cost of your Activase using one of the 4 following drug savings programs: Rx Advantage Card for Activase, Canadian Prescription Savings for Activase, Activase Drug Coupons, Activase Patient Assistance Programs

Question 2

What is Activase?

Accepted Answer

ACTIVASE is the brand name for alteplase IV injection.

Question 3

What dosages is Activase available in?

Accepted Answer

ACTIVASE is available in strengths of 50 mg and 100 mg.

Question 4

What is Activase used for?

Accepted Answer

ACTIVASE is a tissue plasminogen activator (tPA) used for the treatment of:  Acute Ischemic Stroke (AIS) Heart attack Acute Massive Pulmonary Embolism (PE) for lysis

Question 5

How does Activase work?

Accepted Answer

ACTIVASE binds to the fibrin-plasminogen complex in a blood clot and converts the inactive plasminogen into active plasmin which digests the fibrin. ACTIVASE can dissolve a clot in either the coronary or pulmonary artery, restoring the blood supply to the area beyond the blockage.

Question 6

How do I take Activase?

Accepted Answer

ACTIVASE is typically dosed as follows:  Acute Ischemic Stroke: The recommended dose is 0.9 mg/kg (not to exceed 90 mg total dose) infused intravenously over 60 minutes with 10% of the total dose administered as an initial bolus over 1 minute Acute Myocardial Infarction: The recommended total dose is based on patient weight, not to exceed 100 mg Acute Massive Pulmonary Embolism: The recommended dose is 100 mg administered by IV infusion over 2 hours

Question 7

Is it safe for me to take Activase?

Accepted Answer

ACTIVASE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following.  Active internal bleeding Recent intracranial or intraspinal surgery or serious head trauma Intracranial conditions that may increase the risk of bleeding Bleeding diathesis Current severe uncontrolled hypertension Current intracranial hemorrhage History of recent stroke

Question 8

Activase Common Side Effects

Accepted Answer

Common side effects of ACTIVASE:  Bleeding

Question 9

Activase Serious Side Effects

Accepted Answer

Serious side effects are rare with ACTIVASE. Contact your healthcare provider immediately if you experience any of the following.  Severe bleeding Swelling

Question 10

Effects of other drugs, drug classes and over-the-counter products on Activase

Accepted Answer

The following medications may interact with ACTIVASE:  Anticoagulants and drugs that inhibit platelet function increase the risk of bleeding when administered with ACTIVASE therapy Concomitant angiotensin-converting enzyme inhibitors may increase the risk of orolingual angioedema

Question 11

Who makes Activase?

Accepted Answer

Genentech, Inc.

Question 12

Is Activase safe in pregnancy?

Accepted Answer

ACTIVASE may harm your unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with ACTIVASE.

Question 13

What is the generic name for Activase?

Accepted Answer

Alteplase

Question 14

How can NowPatient help me to lower the cost of my Activase prescription?

Accepted Answer

After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your Activase prescription  Rx Advantage Card Drug Coupons Patient Assistance Programs Canadian Prescription Savings  Applicability to each program will be dependent on your insurance status.

Question 15

How do the NowPatient Activase savings programs work?

Accepted Answer

After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.   Rx Advantage Card Drug Coupons Patient Assistance Programs Canadian Prescription Savings  Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.

Question 16

Are the NowPatient Activase savings programs suitable for everyone, regardless of insurance status?

Accepted Answer

No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.      Rx Advantage Card* for Activase Canadian Prescription Savings* for Activase Activase Drug Coupon* Activase Patient Assistance Program*   Insured (federal, state or government) Available Available Not Available Available If Offered by Pharmaceutical Company   Insured (Commercial or Private) Available Available Available If Offered by Pharmaceutical Company Available If Offered by Pharmaceutical Company   Uninsured Available Available Not Available Available If Offered by Pharmaceutical Company   Insured but without pharmacy benefit or drug coverage Available Available Not Available Available If Offered by Pharmaceutical Company     *This is not insurance.

Question 17

Are the NowPatient drug savings programs suitable for brand and generic versions of Activase?

Accepted Answer

No. Each program has applicability requirements. Please see below      Rx Advantage Card* for Activase Canadian Prescription Savings* for Activase Activase Drug Coupon* Activase Patient Assistance Program*   Brand Yes Yes Yes, If Offered by Pharmaceutical Company Yes, If Offered by Pharmaceutical Company   Generic Yes Yes No No     *This is not insurance.

Question 18

If you have Medicare Part D or Medicare Advantage and none of the Activase savings options are applicable or affordable for me, what can you do?

Accepted Answer

If you are insured with Medicare and the Activase drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.  The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication. People who qualify for both Medicare and Medicaid are called ‘dual eligibles’. If you are denied Medicaid for Activase, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

Question 19

I am uninsured or underinsured and none of the Activase prescription saving options are applicable or affordable for me, what can I do?

Accepted Answer

If you are uninsured or underinsured (for example, Activase is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.  The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication. If you are denied and all else fails, and if you have been prescribed Activase for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.

Question 20

I am commercially or privately insured and none of the Activase prescription saving options are applicable or affordable for me, what can I do?

Accepted Answer

If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary. If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov. However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.

Question 21

If I have federal, state or commercial insurance and none of the Activase prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?

Accepted Answer

If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs: 1. Patient Access Network Foundation (PAN) assistance for Activase If you are having trouble paying for your Activase medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for Activase you will need to meet one or all of the following criteria:  Your income is below 400% of the federal poverty level Activase is prescribed for an approved FDA indication You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship You have Medicare insurance coverage that covers Activase If Activase is listed on PAN’s list of covered medications  You can check the Patient Access Network Foundation Website for more information. 2. HealthWell Foundation Copay Program for Activase If you are having trouble paying for your Activase medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for Activase you will need to meet the following criteria:  You live in and are being treated in the United States You are insured and your plan covers Activase If Activase is listed on the HealthWell Foundation’s list of covered medications  You can check the HealthWell Foundation Website for more information. 3. Patient Advocate Foundation Co-Pay Relief Program for Activase Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your Activase treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for Activase you will need to meet the following criteria:  You must be currently insured and have coverage for Activase You must have a confirmed diagnosis and treatment plan You must reside and receive treatment in the United States Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.  You can check the Patient Advocate Foundation Website for more information.

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What is Activase?

What dosages is Activase available in?

What is Activase used for?

How does Activase work?

How do I take Activase?

Is it safe for me to take Activase?

Activase Common Side Effects

Activase Serious Side Effects

Effects of other drugs, drug classes and over-the-counter products on Activase

Who makes Activase?

Is Activase safe in pregnancy?

What is the generic name for Activase?

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