estradiol
Coupons, Savings & Patient Assistance
Learn more about estradiol and see what savings options may be available to you that can help bring down the cost of your medication.
Options may include Rx Advantage Card, Copay assistance & Coupons, or Patient Assistance Programs. Suitable for insured, underinsured or uninsured individuals. Pay as little as $0 per fill.
Manufactured by various FDA-approved generic manufacturers.
This content is intended for US audiences only
Drug savings programs
Learn more about estradiol
What dosages is estradiol available in?
estradiol is available as a 0.5 mg, 1 mg, or 2 mg tablet and a 0.01% vaginal cream.
What is estradiol used for?
estradiol is an estrogen replacement that is used to prevent bone loss and relieve symptoms of menopause, such as hot flashes and vaginal dryness.
How does estradiol work?
estradiol replaces estrogen hormones that your body loses during menopause to relieve symptoms of menopause and prevent bone loss.
How do I take estradiol?
estradiol tablets are typically taken once daily. estradiol cream is typically applied to the vagina daily for 1 to 2 weeks then slowly lowered to 1 gram one to three times a week.
Is it safe for me to take estradiol?
estradiol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not take estradiol if you are a woman who is over 35 years old and smoke. It should also not be used in women with any of the following medical conditions:
- Undiagnosed abnormal vaginal bleeding
- Known, suspected, or history of breast cancer
- Known or suspected estrogen-dependent cancer
- Active or history of deep vein thrombosis or pulmonary embolism
- Stroke or myocardial infarction (heart attack) within the past year
- Liver disease
- Allergy to any of the ingredients in Activella
- Known or suspected pregnancy
estradiol Common Side Effects
Common side effects of estradiol include:
- Headache
- Breast pain or tenderness
- Flu-like symptoms
- Stomach pain
- Swelling
- Back and body pain
- Depression
- Vaginal spotting
- Upset stomach
- Weight gain
- Rashes
- Vaginal discharge
- Itching
- Nausea
estradiol Serious Side Effects
Serious side effects are rare with estradiol. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions
- Heart attack (hest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw)
- Stroke (sudden trouble talking, trouble walking, numbness on one side of your body or face, sudden, severe headaches)
- Shortness of breath
- Breast lumps or pain
- Unusual or heavy vaginal bleeding
- Gallbladder problems (stomach pain, nausea or vomiting that doesn’t go away, fever, yellowing of the skin and eyes)
Effects of other drugs, drug classes and over-the-counter products on estradiol
The following medications may interact with estradiol:
- Inducers of CYP3A4 such as St. John’s wort (Hypericum perforatum) preparations, phenobarbital, carbamazepine, and rifampin may reduce the levels and effects of DOTTI
- Inhibitors of CYP3A4 such as erythromycin, clarithromycin
- ketoconazole, itraconazole, ritonavir and grapefruit juice may increase the levels and effects of estradiol
Who makes estradiol?
Various FDA-approved generic manufacturers
Is estradiol safe in pregnancy?
estradiol should not be used during pregnancy.
What to do if you missed your estradiol dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsWhat can I do if I am commercially insured but cannot afford my estradiol?
If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing estradiol outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.
If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your estradiol without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.
What can I do if I am uninsured and cannot afford my estradiol?
If you cannot afford the cash price of estradiol using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your estradiol without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.
What can I do if I am insured with Medicare and cannot afford my estradiol?
If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:
Option
Savings Information
RX ADVANTAGE CARD
You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.
LOW INCOME SUBSIDY
If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
MEDICAID
Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
Am I eligible for the Rx Advantage Card and how much does estradiol cost without insurance?
Our website gives savings options to customers who wish to purchase estradiol, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.
What will my out-of-pocket cost be for estradiol when using the Rx Advantage Card?
Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for estradiol using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.
Is it legal for me to pay cash for estradiol even though I have insurance?
Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.
Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?
No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket estradiol cash price you pay can be typically cheaper than your plan copay.
Does the Rx Advantage Card work with Commercial Insurance?
We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket estradiol cash price you pay can be typically cheaper than your plan copay.
How do I check prices for estradiol and how do I use the Rx Advantage Card?
You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your estradiol Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.
Do I need to pay for the Rx Advantage Card?
No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.
Is there a estradiol co-pay program?
Generic medications like estradiol do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of estradiol. You can search the brand name of estradiol and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.
Is there a estradiol Patient Assistance Program (PAP)?
Generic medications like estradiol do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of estradiol. You can search the brand name of estradiol and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.
I am insured but I do not qualify for patient assistance or copay assistance for estradiol. Is there any other form of assistance that can help with the costs of my existing copays or co-insurance?
There are a number of resources available such as charitable foundations that may be able to provide assistance for your estradiol:
Patient Access Network Foundation (PAN) assistance for estradiol
If you are having trouble paying for your estradiol medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for estradiol you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- estradiol is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers estradiol
- If estradiol is listed on PAN's list of covered medications
You can check the Patient Access Network Foundation Website for more information.
HealthWell Foundation Copay Program for estradiol
If you are having trouble paying for your estradiol medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for estradiol you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers estradiol
- If estradiol is listed on the HealthWell Foundation's list of covered medications
You can check the HealthWell Foundation Website for more information.
Patient Advocate Foundation Co-Pay Relief Program for estradiol
Patient Advocate Foundation's Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your estradiol treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for estradiol you will need to meet the following criteria:
- You must be currently insured and have coverage for estradiol
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 3000r 4000f the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Can I buy my estradiol from Canada?
Americans pay at least twice as much (in fact 218%) on prescription medications than individuals in other countries, like Canada. The reason why Canada drugs are cheaper is that Canada regulates its prescription medication drug prices (the Patented Medicines Prices Review Board) meaning that consumers pay less for their estradiol. This prevents pharmaceutical patentees from charging excessive prices.
As well, many Canadian drugs are likely produced by exactly the same companies in the same factories, as US prescription drugs.
We have partnered with Prescription Help in Canada that carries thousands of branded and generic medications. If there is an option for estradiol from Canada, then we will provide this as an Rx savings option to you.
Is it safe for me to buy my estradiol from Prescription Help, Canada?
If you purchase estradiol from Canadian Prescription Help, then there is little reason to worry about safety since it is likely that the drugs will be the same ones you would get from your American drugstore, and would have undergone the same rigorous testing as the American counterparts. Canada drugs are regulated for safety, efficacy and quality by Health Canada, which is the Canadian equivalent of the Food and Drug Administration (FDA). If you are unsure, you can discuss this option with your physician, especially if you find it difficult affording your medications and may therefore risk not being treated.
Rest assured, NowPatient has done thorough due diligence on Prescription Help, to ensure that the service is adequately licensed, regulated and safe.
We have checked and verified that Prescription Help:
- Is a licensed pharmacy in Canada.
- Will only fill your estradiol if you have a valid prescription.
- Has a licensed pharmacist on staff to answer your questions.
- Does not send medicine that looks different than what you receive at your usual drug store, nor does it arrive in packaging that is damaged, in a foreign language, has no expiration date, or is expired.
- Does not charge you for products that you never ordered or received.
- Provides clear written protections for your personal and financial information, including credit card numbers.
- Maintains the highest standards of data security and compliance.
- Does not sell your information to other websites.
- Does not supply controlled substances.
- Does not supply any products on an FDA Import Alert.
- Quantities are restricted to a maximum of 3 month's supply for international orders.
- Publishes contact information on website for customer service.
Is ordering estradiol from a Canadian Pharmacy legal?
Although it is technically not legal for individuals to import prescription drugs, It is notable that U.S. government officials have stated that individuals who procure non-controlled prescription drugs from Canada or other foreign sources for up to a three-month supply for their own use are not pursued or prosecuted. There are hundreds of thousands of American patients who have used or continue to use Canadian pharmacies to procure their medications at significant discounts. Often the price of medications can be the difference between getting treated or not being treated.
How do I place an order for estradiol from Prescription Help, Canada?
If your medication is available from our partner Canadian Pharmacy, then we will show it as an option. You can search for the product by pack size, strength or form and then see the price for estradiol. If you are happy with the price, you can proceed to the checkout. This will take you to the Prescription Help website, from where you can complete the process. Prescription Help is not connected to NowPatient other than as an affiliate partner which offers services that may benefit NowPatient users. It is not insurance, any payments are strictly cash and are considered out-of-pocket.
What should I do if I take too much estradiol?
Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using estradiol. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much estradiol. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
What are the benefits of NowPatient?
NowPatient is more than just prescriptions and online pharmacy services. When you join you get access to a range of health services for FREE making NowPatient a perfect companion for helping you lead a healthier life. Join now by either signing up for an account online or downloading the app from the App Store today.
Learn more about all the features you can start benefiting from today!
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Important Information
What does estradiol do in the body?
Will I gain weight on estradiol?
Does estradiol change your mood?
Why does estradiol cause weight gain?
Is estradiol good or bad estrogen?
What does estradiol do to skin?
What not to do when taking estradiol?
What happens when estradiol is low?
How quickly does estradiol work?
What does an estradiol level tell you?
What is the normal range for estradiol levels by age?
What should female estradiol be?
What happens if estradiol is too low?
What does it mean if estradiol is low?
Is low estradiol good or bad?
Why check estradiol levels in females?
What level of estradiol indicates menopause?
What happens if estradiol is too high?
Is high estradiol good for you?
What are common side effects of estradiol?
Do estradiol make you gain weight?
Is estradiol the bad estrogen?
Why should a woman take estradiol?
What are the long term side effects of taking estradiol?
How long is it safe to be on estradiol?
What are the side effects of estradiol in females?
What organ does estradiol affect?
What are the positive side effects of taking estrogen?
Does estradiol cause hair loss?
Is it safe to use estradiol every day?
What happens when you stop taking estradiol?
What are the symptoms of low estradiol?
Is estradiol same as estrogen?
Does estradiol cause weight gain?
What should I avoid while taking estradiol?
What is the best form of estradiol to take?
How long does it take for estradiol to work?
Is 2 mg of estradiol too much?
What happens when you start taking estrogen?
Is estradiol a form of testosterone?
What is NowPatient
Telehealth and Online Pharmacy
NowPatient is a licensed online pharmacy and doctor service that is available around the world. Our service is FREE and packed with valuable features that can benefit your health such as medication reminders, educational blogs, medically approved symptoms checker, UK NHS online pharmacy, private treatment plans, Rx Advantage card, health conditions information, affordable medications options, genetic testing, home test kits, health risks, pollen meter, air quality monitor, weight loss plans, drug savings programs and lots more!
WHY WE BUILT NOWPATIENT
To improve the lives of everyone by making high-quality care accessible and convenient
We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.
Download our app today
Can I trust NowPatient
Meet our medical team
We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process