Key facts about Ubrogepant
What dosages is Ubrogepant available in?
Ubrogepant is available as a 50 mg and 100 mg oral tablet.
What is Ubrogepant used for?
Ubrogepant is a calcitonin gene-related peptide (CGRP) receptor blocker and is used to treat migraine attacks with or without aura in adults.
How does Ubrogepant work?
Ubrogepant is a calcitonin gene-related peptide (CGRP) receptor blocker. High levels of CGRP cause pain and inflammation, which commonly leads to migraines. Ubrogepant blocks CGRP to prevent it from causing pain and inflammation, which leads to relief of migraines.
How do I take Ubrogepant?
Ubrogepant is typically dosed at 50 mg to 100 mg by mouth with or without food when you have a migraine attack. If your migraine doesn’t go away, you can take a second dose at least 2 hours after your first dose. The maximum dose is 200 mg per day. Your dose might differ if you have kidney problems, liver problems, or are taking a medication that interacts with Ubrogepant.
Is it safe for me to take Ubrogepant?
Ubrogepant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are taking a strong CYP3A4 inhibitor.
Ubrogepant Common Side Effects
Common side effects of Ubrogepant:
- Nausea
- Sleepiness
- Dry mouth
Ubrogepant Serious Side Effects
Serious side effects are rare with Ubrogepant. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: hives, rash, blisters, skin reddening, swelling of the lips or tongue, difficulty breathing
Effects of other drugs, drug classes and over-the-counter products on Ubrogepant
The following medications may interact with Ubrogepant:
- Strong CYP3A4 Inducers: Should be avoided as concomitant use will result in reduction of Ubrogepant exposure
Who makes Ubrogepant?
Various FDA-approved generic manufacturers
Is Ubrogepant safe in pregnancy?
Based on animal studies, Ubrogepant may cause fetal harm. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is a pregnancy exposure registry that monitors outcomes in women who become pregnant while taking Ubrogepant. Patients should be encouraged to enroll by calling 1-833-277-0206 or visiting Empress pregnancy registry
