Key facts about Teplizumab-Mzwv
What dosages is Teplizumab-Mzwv available in?
Teplizumab-Mzwv is available as a 2 mg per 2 mL (1 mg/mL) single-dose vial.
What is Teplizumab-Mzwv used for?
Teplizumab-Mzwv is a monoclonal antibody that is used to delay the worsening of Type 1 diabetes from stage 2 to stage 3 in certain people ages 8 years and older.
How does Teplizumab-Mzwv work?
Teplizumab-Mzwv is an anti-CD3 monoclonal antibody that attaches to CD3 proteins found on immune cells. This is thought to help stop the immune cells from attacking and damaging the pancreas. As a result, Teplizumab-Mzwv slow the progression of Type 1 diabetes.
How do I take Teplizumab-Mzwv?
Your prescriber will calculate the dose of Teplizumab-Mzwv based on your body surface area (BSA, in units of m2). It will then be given as a 30-minute infusion through the vein once a day for 14 days.
Is it safe for me to take Teplizumab-Mzwv?
Teplizumab-Mzwv is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Teplizumab-Mzwv Common Side Effects
Common side effects of Teplizumab-Mzwv:
- Low white blood cell counts
- Rash
- Headache
Teplizumab-Mzwv Serious Side Effects
Serious side effects are rare with Teplizumab-Mzwv. Contact your healthcare provider immediately if you experience any of the following:
- Cytokine release syndrome (CRS): fever, nausea, tiredness, headache, muscle or joint pain
- Infection: fever, trouble breathing, cough, weakness, sweating, chills, diarrhea, stomach pain
- Allergic reaction: facial or throat swelling, trouble breathing, hives, rash, vomiting, fever
Effects of other drugs, drug classes and over-the-counter products on Teplizumab-Mzwv
There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes Teplizumab-Mzwv?
Various FDA-approved generic manufacturers
Is Teplizumab-Mzwv safe in pregnancy?
You shouldn’t take Teplizumab-Mzwv during pregnancy. You should also avoid taking it at least 30 days before trying to get pregnant. If you get pregnant within 30 days before treatment or during treatment, tell your prescriber right away. Report the pregnancy to the manufacturer by calling 1-800-633-1610.
