Used for HIV

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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

tenofovir Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is tenofovir available in?

What dosages is tenofovir available in?

tenofovir is available as a 150 mg, 200 mg, 250 mg, and 300 mg oral tablet.

What is tenofovir used for?

What is tenofovir used for?

tenofovir is a HIV ARV and is used for the following:

  • Treatment of HIV infection – people ages 2 years and older
  • Treatment of chronic (long-term) hepatitis B – Brand Viread for people ages 2 years and older; generic for people ages 12 years and older
How does tenofovir work?

How does tenofovir work?

tenofovir is a HIV antiretroviral medication. More specifically a nucleoside reverse transcriptase inhibitors (NRTI). It inserts itself into the genetic material of the virus. As a result, it prevents HIV from making copies of itself and spreading.

How do I take tenofovir?

How do I take tenofovir?

tenofovir is dosed as follows:

  • Adults and children who weigh at least 35 kg (77 lb): The typical dose is 300 mg by mouth once daily
  • Children 2 years and older who weigh at least 17 kg (37 lbs): The dose will depend on your child’s weight. The typical dose is 8 mg/kg of body weight by mouth daily, up to a maximum of 300 mg

Your dose might differ if you have kidney problems.

Is it safe for me to take tenofovir?

Is it safe for me to take tenofovir?

tenofovir is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

tenofovir Common Side Effects

tenofovir Common Side Effects

Common side effects of tenofovir:

  • Higher cholesterol levels
  • Higher creatine kinase levels
  • Feeling tired
  • Depression
  • Nausea
  • Diarrhea
  • Dizziness
  • Rash
  • Headache
tenofovir Serious Side Effects

tenofovir Serious Side Effects

Serious side effects are rare with tenofovir. Contact your healthcare provider immediately if you experience any of the following.

  • Build up of lactic acid in the blood: feeling more tired and weak, belly pain, muscle pain, breathing problems
    Serious kidney problems: tiredness, confusion, nausea, urinating less than usual, swelling in your legs, ankles, or feet, joint pain, bone pain
  • Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool
Effects of other drugs, drug classes and over-the-counter products on tenofovir

Effects of other drugs, drug classes and over-the-counter products on tenofovir

The following medications may interact with tenofovir:

  • Tenofovir disoproxil fumarate increases didanosine concentrations
  • Dose reduction and close monitoring for didanosine toxicity are warranted
  • Coadministration decreases atazanavir concentrations. When coadministered with tenofovir, use atazanavir given with ritonavir
  • Coadministration of tenofovir with certain HIV-1 protease inhibitors or certain drugs to treat HCV increases tenofovir concentrations
  • Monitor for evidence of tenofovir toxicity
  • Consult Full Prescribing Information prior to and during treatment for important drug interactions
Who makes tenofovir?

Who makes tenofovir?

Various FDA-approved generic manufacturers

Is tenofovir safe in pregnancy?

Is tenofovir safe in pregnancy?

It is not known if tenofovir will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking tenofovir. There is a pregnancy registry for women who take tenofovir during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry.


What to do if you missed your tenofovir dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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