Temozolomide Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Temozolomide
    Generic for Temodar
    30 capsules $311.7 USD
    Save $3051.90
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Do you need a prescription for temozolomide?

Yes, temozolomide is only available with a valid physician Rx.

How much is temozolomide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase temozolomide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for temozolomide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a temozolomide savings card?

Yes. Save up to 90% on your temozolomide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a temozolomide coupon provider in the US?

No. Now Patient does not provide temozolomide coupons or FREE temozolomide samples.

Do you accept commercial, Medicare or Medicaid coverage for temozolomide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much temozolomide?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using temozolomide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much temozolomide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic temozolomide?

Generic temozolomide (TMZ) refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of temozolomide

Temozolomide is approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain types of brain tumours, including glioblastoma multiforme and anaplastic astrocytoma.

Active ingredient of temozolomide

The active ingredient of temozolomide is temozolomide.

US brand name of temozolomide and manufacturer

Temozolomide is available in the US under the brand name Temodar. It is manufactured by Merck & Co., Inc.

UK brand name of temozolomide and manufacturer

In the UK, temozolomide is available under various brand names, including Temodal and temozolomide. The manufacturer may vary depending on the brand name.

Prescription requirement for temozolomide

A prescription (Rx) is required for temozolomide in both the US and the UK.

Availability of temozolomide in the UK with NHS prescription

Temozolomide is available in the UK with an NHS prescription.

Conditions treated by temozolomide

Temozolomide is primarily used for the treatment of certain types of brain cancer, including glioblastoma multiforme (in combination with radiotherapy in patients newly-diagnosed with cancer and then alone) and anaplastic astrocytoma (in patients with refractory cancer that has worsened during therapy with nitrosourea and procarbazine). It has also been shown to be effective against melanomas.

How does temozolomide work?

Temozolomide is an alkylating agent that works by damaging the DNA of cancer cells, inhibiting their growth and causing them to die. It is specifically designed to target rapidly dividing cells, such as cancer cells.

Forms of temozolomide available

Temozolomide is available in the form of oral capsules.

Dosage of temozolomide

The dosage of temozolomide may vary depending on the individual’s condition, medical history, and response to the medication. It is important to follow the drug information and patient information provided by the healthcare provider.

Directions for temozolomide use

Temozolomide should be taken exactly as directed by the healthcare provider. Take temozolomide capsules on an empty stomach with a glass of water. It is important to swallow the capsules whole and avoid chewing or crushing them.

Warnings and precautions for temozolomide

  • Temozolomide may cause certain side effects, including nausea, vomiting, fatigue, and a decrease in blood cell counts. It may also increase the risk of developing other types of cancer
  • Tell your doctor if you are allergic to temozolomide or dacarbazine before starting treatment
  • Your will be monitored for your full blood counts and bone marrow function while taking temozolomide
  • Use birth control to prevent pregnancy while taking temozolomide. If you become pregnant, speak to your doctor for medical advice
  • This medication passes into breast milk. Speak to your doctor if you are planning to breastfeed

Possible side effects of temozolomide

In clinical trials common side effects of temozolomide may include nausea, vomiting, fatigue, constipation, loss of appetite, and hair loss. Serious side effects are possible but less common. Serious side effects include signs of infection such as fever, sore throat, and ongoing cough. Promptly report signs of an allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, chest pain, swelling of the face, tongue or throat, skin rash, and severe skin reactions.

Interactions with other drugs

Temozolomide may interact with other medications, including live vaccines. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to temozolomide

Other chemotherapeutic agents used for the treatment of brain tumors include carmustine, lomustine, and temozolomide with other chemotherapy drugs.


  • FDA Prescribing Information for Temozolomide
  • MHRA product information for Temozolomide
  • WebMD – Temozolomide
  • Drugs.com – Temozolomide
  • NHS UK
Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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