View TAPAZOLE savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or TAPAZOLE Patient Assistance Program.

Programs are suitable for individuals who want to buy TAPAZOLE without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Pfizer

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

    A hand holding a dark-colored prescription savings card with various ID numbers and the label "Rx Advantage." Text below states the card is not insurance and cannot be used for Medicare or Medicaid.

    Save up to 90%

  • Available

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Prescription Help Logo
  • Unavailable

    Drug Coupons

    A hand holds a Copay Savings Card that states eligible patients with commercial insurance may pay as little as $0 per tube for Opzelura.
  • Unavailable

    Patient Assistance Programs

    A picture of a patient assistance application form
Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about TAPAZOLE



TAPAZOLE is the brand name for methimazole and is available as an oral tablet.

What dosages is TAPAZOLE available in?

What dosages is TAPAZOLE available in?

TAPAZOLE is available as a 5 mg and 10 mg oral tablet.

What is TAPAZOLE used for?

What is TAPAZOLE used for?

TAPAZOLE is an antithyroid agent that is used to treat high thyroid hormone levels (hyperthyroidism) in people:
With Graves’ disease or other medical conditions who can’t receive thyroid surgery or radioactive iodine treatment
Who are preparing to undergo thyroid surgery or radioactive iodine treatment

How does TAPAZOLE work?

How does TAPAZOLE work?

TAPAZOLE belongs to a class of medications called antithyroids. It works by blocking the thyroid gland from making thyroid hormones. Thyroid hormones help regulate your body temperature, control how your body uses energy, and keep your organ systems working well. But having too much thyroid hormone in your body can cause unpleasant symptoms, including weight loss, irregular heartbeat, frequent bowel movements, an enlarged thyroid gland, and feeling hot when others don’t. By blocking your thyroid from making these hormones, TAPAZOLE helps to bring your thyroid hormone levels down to a healthy level. This will help relieve your symptoms and give you more energy throughout the day.

How do I take TAPAZOLE?

How do I take TAPAZOLE?

Your dose depends on whether you’re starting or continuing therapy. Your provider will adjust your continuing dose throughout treatment based on your thyroid hormone levels.
Adults: The typical starting dose ranges from 15 mg to 60 mg per day, depending on how severe your hyperthyroidism is. The total daily dose is split into 3 smaller doses that are taken by mouth every 8 hours. Once your thyroid hormone levels become normal, you’ll continue treatment at a maintenance dose that typically ranges from 5 mg to 15 mg taken once a day. Children: The dose will depend on your child’s body weight. The typical starting dose is 0.4 mg/kg of body weight per day. This total dose is split into 3 smaller doses given by mouth every 8 hours. The typical maintenance dose is about half of the starting dose.

Is it safe for me to take TAPAZOLE?

Is it safe for me to take TAPAZOLE?

TAPAZOLE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

TAPAZOLE Common Side Effects

TAPAZOLE Common Side Effects

Common side effects of TAPAZOLE:

  • Raised, itchy rash
  • Nausea
  • Vomiting
  • Stomach upset
  • Loss of taste
  • Unusual hair loss
  • Drowsiness
TAPAZOLE Serious Side Effects

TAPAZOLE Serious Side Effects

Serious side effects are rare with TAPAZOLE. Contact your healthcare provider immediately if you experience any of the following.

  • Low white blood cells (agranulocytosis): fever, fatigue, chills, sore throat
  • Inflamed blood vessels (vasculitis): rash, nerve pain, chest pain, stomach pain
  • Unusual bleeding or bruising: black stools, blood in urine, bleeding or bruising that doesn’t go away
  • Liver problems: upper right stomach pain, loss of appetite, yellowing of skin or whites of eyes (jaundice)
Effects of other drugs, drug classes and over-the-counter products on TAPAZOLE

Effects of other drugs, drug classes and over-the-counter products on TAPAZOLE

The following medications may interact with TAPAZOLE:

  • Anticoagulants (oral):
  • Due to potential inhibition of vitamin K activity by methimazole, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures
  • β-adrenergic blocking agents:
  • Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. A dose reduction of beta-adrenergic blockers may be needed when a hyperthyroid patient becomes euthyroid
  • Digitalis glycosides
  • Serum digitalis levels may be increased when hyperthyroid patients on a stable digitalis glycoside regimen become euthyroid; a reduced dosage of digitalis glycosides may be needed
  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed
Who makes TAPAZOLE?

Who makes TAPAZOLE?


Is TAPAZOLE safe in pregnancy?

Is TAPAZOLE safe in pregnancy?

Because of the risk for congenital malformations associated with use of TAPAZOLE in the first trimester of pregnancy, it may be appropriate to use other agents in pregnant women requiring treatment for hyperthyroidism. If TAPAZOLE is used, the lowest possible dose to control the maternal disease should be given.


What to do if you missed your TAPAZOLE dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

People Asked

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Telehealth and Online Pharmacy

NowPatient is a licensed online pharmacy and doctor service that is available around the world. Our service is FREE and packed with valuable features that can benefit your health such as medication reminders, educational blogs, medically approved symptoms checker, UK NHS online pharmacyprivate treatment plansRx Advantage cardhealth conditions information, affordable medications options, genetic testinghome test kitshealth riskspollen meterair quality monitor, weight loss plans, drug savings programs and lots more!

A laptop screen displaying a health dashboard with widgets showing health profile, notifications, personalized health tools, and favorite widgets including body mass index and weight loss tracking.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers