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Suvorexant is available as 5 mg, 10 mg, 15 mg, and 20 mg oral tablet.

Suvorexant is an orexin receptor antagonist and is used to treat insomnia.

Suvorexant is a newer, non-benzodiazepine option that works by blocking the action of orexin. Orexin is a chemical in the brain that plays a role in the sleep cycle and promotes wakefulness. By blocking this chemical, it can help promote sleep in people with insomnia.

Suvorexant is typically started at 10 mg by mouth within 30 minutes of bedtime. If you’re still having trouble falling sleep, your provider may raise your dose to 20 mg by mouth at bedtime; that’s the maximum daily dose.

Suvorexant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. BELSOMRA is contraindicated in patients with narcolepsy.

Common side effects of Suvorexant:

• Drowsiness the day after taking the medication

Serious side effects are rare with Suvorexant. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reaction
• Worsening depression
• Suicidal thoughts

The following medications may interact with Suvorexant:

• CYP3A inhibitors: Recommended dose is 5 mg when used with moderate CYP3A inhibitors. Dose can be increased to 10 mg once per night if the 5 mg dose is not effective.
• Not recommended for use in patients taking strong CYP3A inhibitors
• Strong CYP3A inducers: Efficacy may be reduced
• Digoxin: Monitor digoxin concentrations

Various FDA-approved generic manufacturers

It is not known if Suvorexant can harm your unborn baby.
Suvorexant should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.

• Belsomra C-Iv