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MEDICAL INFORMATION
Sulfamethoxazole Key Facts
What dosages is Sulfamethoxazole available in?
Sulfamethoxazole is available as an oral tablet that contains 400 mg of sulfamethaxozole and 80 mg of trimethoprim or 800 mg of sulfamethaxozole and 160 mg of trimethoprim.
What is Sulfamethoxazole used for?
Sulfamethoxazole is a combination antibiotic that is used to treat bacterial infections such as urinary tract infections, ear infections, lower respiratory tract infections, travelers’ diarrhea, and diarrhea caused by Shigella (Shigellosis).
How does Sulfamethoxazole work?
Sulfamethoxazole is an antibiotic that contains two medications, Sulfamethoxazole and trimethoprim. They work together to stop bacteria from being able to make a chemical (folic acid) that’s needed for them to grow and survive.
How do I take Sulfamethoxazole?
Sulfamethoxazole is typically taken by mouth twice a day for 5 to 14 days, depending on the infection being treated. Your dose might be different if you have kidney problems.
Is it safe for me to take Sulfamethoxazole?
Sulfamethoxazole is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are allergic to sulfonamides, have megaloblastic anemia due to folate deficiency, are less than 2 months of age, or have severe liver or kidney impairment.
Sulfamethoxazole Common Side Effects
Common side effects of Sulfamethoxazole include:
- Nausea
- Vomiting
- Diarrhea
- Loss of appetite
- Rash
- Hives
- Changes to blood sugar
- Skin sensitivity to sun or light
Sulfamethoxazole Serious Side Effects
Serious side effects are rare with Sulfamethoxazole.
Effects of other drugs, drug classes and over-the-counter products on Sulfamethoxazole
The following medications may interact with Sulfamethoxazole:
- Thiazides diurectics – An increased incidence of thrombocytopenia with purpura has been reported
- Warfarin – Prolonged prothrombin time
- Phenytoin – May block the metabolism and increase the effects of phenytoin.Sulfamethoxazole may inhibit the hepatic metabolism of phenytoin (a CYP2C9 substrate)
- Methotrexate – May increase the effects of methotrexate
- Cyclosporine – May increase the risk of reversible nephrotoxicity in renal transplant recipients
- Digoxin – Increased digoxin blood levels can occur with concomitant Sulfamethoxazole therapy
- Indomethacin – Increased Sulfamethoxazole blood levels may occur in patients who are also receiving indomethacin
- TCAs – The efficacy of tricyclic antidepressants (TCAs) can decrease when coadministered with Sulfamethoxazole
Who makes Sulfamethoxazole?
Various FDA-approved generic manufacturers
Is Sulfamethoxazole safe in pregnancy?
Sulfamethoxazole is not recommend to be used if you are pregnant as it may cause harm to your unborn baby. If you’re pregnant, make sure to tell your physician because they’ll most likely prescribe a different antibiotic for you.
What is the brand name for Sulfamethoxazole?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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