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Silver Sulfadiazine is available as a 1% topical cream.

Silver Sulfadiazine is an antibiotic and is used to prevent and treat infections caused by second- and third-degree burns.

Silver Sulfadiazine kills multiple types of bacteria by damaging their protective coverings.

Silver Sulfadiazine is typically applied as a thin layer to the burn(s) one to two times a day. Apply enough silver Silver Sulfadiazine to cover the affected area(s) completely and evenly. If needed, apply more cream to replace any medication that has come off on bandages, clothing, or bed linens. Typically, your provider will ask you to continue treatment until the burn area has healed or is ready for grafting.

Silver Sulfadiazine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Silver Sulfadiazine should not be used on pregnant women approaching or at term, on premature infants,
or on newborn infants during the first 2 months of life.

Common side effects of Silver Sulfadiazine:

• Temporary low number of white blood cells

Serious side effects are rare with Silver Sulfadiazine. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reaction: rash, changes in skin color, itchiness, raised skin areas
• Severe skin reactions: worsening skin pain, fever, blisters or sores, peeling skin

• There are no major drug interactions listed for Silver Sulfadiazine. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Various FDA-approved generic manufacturers

Silver Sulfadiazine should not be used on pregnant women approaching or at term, on premature infants, or on newborn infants during the first 2 months of life.

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