Silver sulfadiazine

Silver sulfadiazinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Silver Sulfadiazine
    Generic for SSD
    20g tube of creams $7.89 USD
    Save $9.27
  3. Silver Sulfadiazine
    Generic for SSD
    50g jar of creams $7.78 USD
    Save $9.38
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Do you need a prescription for silver sulfadiazine?

Yes, silver sulfadiazine is only available with a valid physician Rx.

How much is silver sulfadiazine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase silver sulfadiazine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for silver sulfadiazine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a silver sulfadiazine savings card?

Yes. Save up to 90% on your silver sulfadiazine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a silver sulfadiazine coupon provider in the US?

No. Now Patient does not provide silver sulfadiazine coupons or FREE silver sulfadiazine samples.

Do you accept commercial, Medicare or Medicaid coverage for silver sulfadiazine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much silver sulfadiazine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using silver sulfadiazine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much silver sulfadiazine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic Silver sulfadiazine?

Generic silver sulfadiazine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of silver sulfadiazine

Silver sulfadiazine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of burns.

Active ingredient of silver sulfadiazine

The active ingredient of silver sulfadiazine is silver sulfadiazine.

US brand name of silver sulfadiazine and manufacturer

Silver sulfadiazine cream is available in the US under the brand name Silvadene, SSD, and, Thermazene. It is manufactured by various pharmaceutical companies.

UK brand name of silver sulfadiazine and manufacturer

In the UK, silver sulfadiazine is available under various brand names, including Flamazine and generic versions. The manufacturer may vary depending on the brand name.

Prescription requirement for silver sulfadiazine

A prescription (Rx) is required for silver sulfadiazine in both the US and the UK.

Availability of silver sulfadiazine in the UK with NHS prescription

Silver sulfadiazine is available in the UK with an NHS prescription.

Conditions treated by silver sulfadiazine

Silver sulfadiazine is a sulfa drug, primarily used to prevent and treat wound infections in second and third-degree burns. It is applied topically to the burned areas to prevent or treat infections.

How does silver sulfadiazine work?

Silver sulfadiazine works by releasing silver ions that have antimicrobial properties. These ions help to prevent and treat infections by inhibiting the growth of various bacteria and fungi commonly found in burn wounds.

Forms of silver sulfadiazine available

Silver sulfadiazine is available in the form of a cream or ointment for topical application.

Directions for silver sulfadiazine use

Silver sulfadiazine topical cream should be applied directly to the burn wound as directed by the healthcare provider. It is usually applied once or twice daily, following proper wound cleaning and debridement.

Warnings and contraindications for silver sulfadiazine

  • Silver sulfadiazine topical antibacterial should not be used in individuals with a known allergy to sulfonamides or silver
  • Use caution when applying silver sulfadiazine to large affected areas of the body or in patients with renal impairment, as the medication may be absorbed into the bloodstream and can cause side effects
  • Tell your doctor if you have an enzyme deficiency (G6PD or glucose-6-phosphate dehydrogenase), kidney disease, liver problems, or a low white blood cell count

Use of silver sulfadiazine during pregnancy and breastfeeding

The use of silver sulfadiazine in pregnant women and during breastfeeding should be discussed with a healthcare provider. It may be used if the potential benefits outweigh the risks.

Possible side effects of silver sulfadiazine

Common side effects of silver sulfadiazine may include temporary skin discoloration, itching, and burning or stinging at the application site. Serious side effects include, signs of infection (sore throat, fever, chills), signs of anemia (such as unusual tiredness, weakness, fast heartbeat), kidney problems, and liver problems. Get medical help right away if you have an allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, chest pain, swelling of the face, tongue or throat, skin rash, and severe skin reactions. Promptly report any adverse effects to a healthcare professional for medical advice.

Interactions with other drugs

Silver sulfadiazine may interact with certain medications. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medication, supplements, and vitamins you are taking to avoid potential adverse reactions and drug interactions.

Similar drugs to silver sulfadiazine

Other topical antimicrobial agents used for the treatment of burns include mafenide acetate and bacitracin.


Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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