View SAPHNELO savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or SAPHNELO Patient Assistance Program.

Programs are suitable for individuals who want to buy SAPHNELO without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by AstraZeneca

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about SAPHNELO



SAPHNELO is the brand name for anifrolumab-fnia and is available as an IV infusion.

What dosages is SAPHNELO available in?

What dosages is SAPHNELO available in?

SAPHNELO is available in a 300 mg/2 mL (150 mg/mL) in a single-dose vial.

What is SAPHNELO used for?

What is SAPHNELO used for?

SAPHNELO is a biologic medication that is used as an add-on therapy for moderate-to-severe systemic lupus erythematosus (SLE).

How does SAPHNELO work?

How does SAPHNELO work?

SAPHNELO is a biologic medication. It attaches to certain proteins in your immune system that play a role in SLE. By attaching to these proteins, it stops them from turning on and blocks inflammatory pathways in your body.

How do I take SAPHNELO?

How do I take SAPHNELO?

The typical dose of SAPHNELO is 300 mg injected into the veins (IV) once every month. It’s given as an infusion over 30 minutes.

Is it safe for me to take SAPHNELO?

Is it safe for me to take SAPHNELO?

SAPHNELO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

SAPHNELO Common Side Effects

SAPHNELO Common Side Effects

Common side effects of SAPHNELO:

  • Upper respiratory infection
  • Bronchitis
  • Infusion-related reactions (headache, dizziness, nausea)
  • Herpes zoster infection (shingles)
  • Cough
SAPHNELO Serious Side Effects

SAPHNELO Serious Side Effects

Serious side effects are rare with SAPHNELO. Contact your healthcare provider immediately if you experience any of the following.

Severe infection: confusion, fever, difficulty breathing, weakness, cough, sweating, chills, stomach pain, diarrhea, burning sensation when you urinate
Serious allergic reaction (anaphylaxis): difficulty breathing, tightness in the throat, hives, itching, fast heartbeat, nausea, dizziness, lightheadedness, swelling in the face or tongue

Effects of other drugs, drug classes and over-the-counter products on SAPHNELO

Effects of other drugs, drug classes and over-the-counter products on SAPHNELO

There are no major drug interactions listed for SAPHNELO. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes SAPHNELO?

Who makes SAPHNELO?


Is SAPHNELO safe in pregnancy?

Is SAPHNELO safe in pregnancy?

It is not known if SAPHNELO will harm your unborn baby. Tell your healthcare provider
if you are pregnant, think you might be pregnant, or plan to become pregnant during your treatment with SAPHNELO.
If you become pregnant while receiving SAPHNELO, talk to your healthcare provider.
A pregnancy exposure registry monitors pregnancy outcomes in women exposed to SAPHNELO. You can find out more
information about the registry by calling AstraZeneca at 1-877-693-9268.


What to do if you missed your SAPHNELO dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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