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Manufactured by Lundbeck

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

SABRIL TABLETS Uses, Side Effects, Interactions, Warnings & Dosing



SABRIL TABLETS is the brand name for vigabatrin oral tablets.

What dosages is SABRIL TABLETS available in?

What dosages is SABRIL TABLETS available in?

SABRIL TABLETS is available as a 500 mg oral tablet.

What is SABRIL TABLETS used for?

What is SABRIL TABLETS used for?

SABRIL TABLETS is an antiepileptic and is used for the following:

  • Difficult-to-treat complex partial seizures in people age 2 years and older (as add-on therapy to other medications)
    Infantile spasms in children age 1 month to 2 years
How does SABRIL TABLETS work?

How does SABRIL TABLETS work?

SABRIL TABLETS is an antiepileptic (another name for anti-seizure medication). It’s not exactly clear how it works to treat seizures. But it’s thought to raise the levels of gamma-aminobutyric acid (GABA), a chemical in the brain that calms nerves. This helps control seizures.



SABRIL TABLETS is dosed as follows: The dose is the same for the tablet and powder for liquid.

Complex partial seizures

  • Age 17 years or older: The typical dose is 500 mg to 1,500 mg by mouth twice per day
  • Age 2 to less than 17 years: The dose is based on your child’s body weight
  • 22 to 33 pounds: The typical dose is 175 mg to 525 mg by mouth twice per day
  • 33 to 44 pounds: The typical dose is 225 mg to 650 mg by mouth twice per day
  • 44 to 55 pounds: The typical dose is 250 mg to 750 mg by mouth twice per day
  • 55 to 132 pounds: The typical dose is 250 mg to 1,000 mg by mouth twice per day
  • Greater than 132 pounds: The typical dose is 500 mg to 1,500 mg by mouth twice per day
  • Infantile spasms: The dose is based on your child’s body weight. The starting dose is 25 mg/kg by mouth twice per day. The maximum dose is 75 mg/kg twice per day

Your provider will change the dose depending on how well the medication is working for you and if you’re having side effects. Your dose might differ if you have kidney problems.

Is it safe for me to take SABRIL TABLETS?

Is it safe for me to take SABRIL TABLETS?

SABRIL TABLETS is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

SABRIL TABLETS Common Side Effects

SABRIL TABLETS Common Side Effects

Common side effects of SABRIL TABLETS:

  • Headache
  • Dizziness
  • Tiredness
  • Drowsiness
  • Uncontrolled shaking
  • Common cold symptoms
  • Blurred vision
  • Eye twitching
  • Diarrhea
  • Nausea
  • Joint pain
  • Abnormal coordination
  • Weight gain
  • Upper respiratory tract infection
SABRIL TABLETS Serious Side Effects

SABRIL TABLETS Serious Side Effects

Serious side effects are rare with SABRIL TABLETS. Contact your healthcare provider immediately if you experience any of the following.

  • Permanent vision loss
  • Suicidal thoughts or behaviors
Effects of other drugs, drug classes and over-the-counter products on SABRIL TABLETS

Effects of other drugs, drug classes and over-the-counter products on SABRIL TABLETS

The following medications may interact with SABRIL TABLETS:

  • Decreased phenytoin plasma levels: dosage adjustment may be needed



Is SABRIL TABLETS safe in pregnancy?

Is SABRIL TABLETS safe in pregnancy?

SABRIL TABLETS can cause harm to your unborn baby. You and your healthcare provider will have to decide if you should take SABRIL TABLETS while you are pregnant.
Pregnancy Registry: If you become pregnant while taking SABRIL TABLETS, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. Information on the registry can also be found at the website AED pregnancy registry . The purpose of this registry is to collect information about the safety of antiepileptic medicine during pregnancy.


What to do if you missed your SABRIL TABLETS dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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