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rituximab/hyaluronidase human

rituximab/hyaluronidase human

Used for Cancer

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Manufactured by various FDA-approved generic manufacturers.

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This content is intended for US audiences only

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rituximab/hyaluronidase human Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is rituximab/hyaluronidase human available in?

What dosages is rituximab/hyaluronidase human available in?

rituximab/hyaluronidase human is available as a single dose vial containing one of the following:

  • 1,400 mg rituximab and 23,400 Units hyaluronidase human per 11.7 mL (120 mg/2,000 Units per mL)
  • 1,600 mg rituximab and 26,800 Units hyaluronidase human per 13.4 mL (120 mg/2,000 Units per mL)
What is rituximab/hyaluronidase human used for?

What is rituximab/hyaluronidase human used for?

rituximab/hyaluronidase human is monoclonal antibody that is used to treat:

Blood cancers

  • Certain types of CD20-positive non-Hodgkin’s lymphoma (NHL) in adults and children ages 6 months and older
  • CD20-positive chronic lymphocytic leukemia (CLL) in adults

Autoimmune conditions

  • Moderate to severe rheumatoid arthritis (RA) in adults
    Granulomatosis with polyangitis (GPA) and microscopic polyangitis (MPA) in adults and children ages 2 years and older
  • Moderate to severe pemphigus vulgaris in adults
How does rituximab/hyaluronidase human work?

How does rituximab/hyaluronidase human work?

rituximab/hyaluronidase human is a monoclonal antibody. It targets specific immune cells called B cells that can be involved in a range of different health conditions. For example, B cells sometimes turn into cancer cells. Other times, they become overly active and cause autoimmune conditions. rituximab/hyaluronidase human works by attaching a specific protein on the B cells called CD20. When it does so, it signals to the body to attack and kill that cell. As a result, these abnormal or overly active B cells can’t grow, spread, or work as well.

How do I take rituximab/hyaluronidase human?

How do I take rituximab/hyaluronidase human?

All patients must receive at least one full dose of a rituximab product by intravenous infusion before receiving rituximab/hyaluronidase human by subcutaneous injection.

Is it safe for me to take rituximab/hyaluronidase human?

Is it safe for me to take rituximab/hyaluronidase human?

rituximab/hyaluronidase human is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

rituximab/hyaluronidase human Common Side Effects

rituximab/hyaluronidase human Common Side Effects

Common side effects of rituximab/hyaluronidase human:

  • Fever
  • Lower white blood cell counts
  • Chills
  • Infection
  • Weakness
  • Nausea
  • Headache
  • Night sweats
  • Rash
rituximab/hyaluronidase human Serious Side Effects

rituximab/hyaluronidase human Serious Side Effects

Serious side effects are rare with rituximab/hyaluronidase human.

Effects of other drugs, drug classes and over-the-counter products on rituximab/hyaluronidase human

Effects of other drugs, drug classes and over-the-counter products on rituximab/hyaluronidase human

The following medications may interact with rituximab/hyaluronidase human:

  • Renal toxicity when used in combination with cisplatin.
Who makes rituximab/hyaluronidase human?

Who makes rituximab/hyaluronidase human?

Various FDA-approved generic manufacturers

Is rituximab/hyaluronidase human safe in pregnancy?

Is rituximab/hyaluronidase human safe in pregnancy?

rituximab/hyaluronidase human may harm your unborn baby. Females who are able to become pregnant: Your healthcare provider should check to see if you are pregnant before you receive rituximab/hyaluronidase human. You should use effective birth control (contraception) during treatment with rituximab/hyaluronidase human and for 12 months after the last dose of rituximab/hyaluronidase human. Talk to your healthcare provider about effective birth control. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with rituximab/hyaluronidase human.

What is the brand name for rituximab/hyaluronidase human?

What is the brand name for rituximab/hyaluronidase human?

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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