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RETACRIT Uses, Side Effects, Interactions, Warnings & Dosing



RETACRIT is the brand name for epoetin alfa-epbx and is available as an injection for subcutaneous or IV use.

What dosages is RETACRIT available in?

What dosages is RETACRIT available in?

RETACRIT is available as a 2,000 Units/mL, 3,000 Units/mL, 4,000 Units/mL, 10,000 Units/mL, and 40,000 Units/mL single-dose vial or a 20,000 Units/2 mL (10,000 Units/mL) and 20,000 Units/mL multiple-dose vial.

What is RETACRIT used for?

What is RETACRIT used for?

RETACRIT is an erythropoiesis-stimulating agent (ESA) that is used for the:

  • Treatment of anemia due to chemotherapy, chronic kidney disease, and zidovudine use in HIV-infected patients
  • Reduction of allogeneic red blood cell transfusions in patients having elective, noncardiac, nonvascular surgery
How does RETACRIT work?

How does RETACRIT work?

RETACRIT is an erythropoiesis-stimulating agent (ESA). It works similarly to a naturally-occurring hormone in our body (erythropoietin). Erythropoietin sends a signal to our body to make more red blood cells.

How do I take RETACRIT?

How do I take RETACRIT?

The dose of RETACRIT will be calculated based on your condition and weight. It can be given every day, 3 times a week, or once a week.

Is it safe for me to take RETACRIT?

Is it safe for me to take RETACRIT?

RETACRIT is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • Uncontrolled hypertension
  • Pure red cell aplasia (PRCA) that begins after treatment with RETACRIT or other erythropoietin protein drugs.
  • Serious allergic reactions to RETACRIT or other epoetin alfa products
  • Use of the multiple-dose vials containing benzyl alcohol in neonates, infants, pregnant women, and lactating women
RETACRIT Common Side Effects

RETACRIT Common Side Effects

Common side effects of RETACRIT:

  • High blood pressure
  • Joint pain
  • Fever
  • Dizziness
  • Blood clot at dialysis port
  • Upper respiratory tract infection
RETACRIT Serious Side Effects

RETACRIT Serious Side Effects

Serious side effects are rare with RETACRIT. Contact your healthcare provider immediately if you experience any of the following.

  • Blood clot (redness, swelling, pain usually in one leg)
Effects of other drugs, drug classes and over-the-counter products on RETACRIT

Effects of other drugs, drug classes and over-the-counter products on RETACRIT

There are no major drug interactions listed for RETACRIT. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes RETACRIT?

Who makes RETACRIT?


Is RETACRIT safe in pregnancy?

Is RETACRIT safe in pregnancy?

It is not known if RETACRIT may harm your unborn baby. Talk to your healthcare provider about possible pregnancy and birth control choices that are right for you. Do not use RETACRIT from multiple-dose vials in newborns, infants, pregnant or breastfeeding women because the RETACRIT in these vials contains benzyl alcohol. Benzyl alcohol has been shown to cause brain damage, other serious side effects, and death in newborn and premature babies. If you use RETACRIT from multiple-dose vials you should not breastfeed for at least 2 weeks after the last dose.


What to do if you missed your RETACRIT dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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