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Raloxifene is available as a 60 mg oral tablet.

Raloxifene is a selective estrogen receptor modulator (SERM) and is used to treat osteoporosis in women who’ve gone through menopause (postmenopausal), and lower the risk of invasive breast cancer in postmenopausal women who are at high risk for breast cancer or who have osteoporosis.

Raloxifene is a selective estrogen receptor modulator (SERM). It either acts like estrogen or blocks the activity of estrogen, depending on where the medication works in the body. In your bones, Raloxifene acts like estrogen. This helps prevent bone breakdown and improve bone mineral density (BMD), which is a measure of how dense your bones are. A higher BMD means your bones are stronger, which helps lower your risk of bone fractures. In your breast, Raloxifene blocks estrogen from entering cells. This prevents estrogen from turning on signals that make breast cells cancerous.

Raloxifene is typically taken by mouth once daily.

Raloxifene is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an active or past history of venous thromboembolism, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis or are pregnant.

Common side effects of Raloxifene include:

• Joint pain
• Flu-like symptoms
• Hot flashes
• Bronchitis
• Runny nose
• Cough
• Headache
• Nausea
• Sinus infection
• Leg cramps
• Diarrhea
• Swelling in the arms or legs

Serious side effects are rare with Raloxifene. Contact your healthcare provider immediately if you experience any of the following.

• Blood clot: leg pain or swelling, skin that’s warm to the touch, trouble breathing
• Stroke: sudden weakness on one side of the body, confusion, severe headache, changes in speech or vision

The following medications may interact with Raloxifene:

• Cholestyramine – Use with Raloxifene is not recommended. Reduces the absorption and enterohepatic cycling of Raloxifene
• Warfarin – Monitor prothrombin time when starting or stopping Raloxifene
• Highly Protein-Bound Drugs- Use with Raloxifene with caution. Highly protein-bound drugs include diazepam, diazoxide, and
• lidocaine

Various FDA-approved generic manufacturers

Raloxifene is contraindicated for use in pregnancy, as it may cause fetal harm.

• Evista