Raloxifene Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Raloxifene HCl
    Generic for Evista
    30 tablets $6.6 USD
    Save $169.20
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Do you need a prescription for raloxifene?

Yes, raloxifene is only available with a valid physician Rx.

How much is raloxifene without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase raloxifene, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for raloxifene in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a raloxifene savings card?

Yes. Save up to 90% on your raloxifene with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a raloxifene coupon provider in the US?

No. Now Patient does not provide raloxifene coupons or FREE raloxifene samples.

Do you accept commercial, Medicare or Medicaid coverage for raloxifene in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much raloxifene?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using raloxifene. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much raloxifene. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic raloxifene?

Generic raloxifene refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of raloxifene

Raloxifene is approved by the U.S. Food and Drug Administration (FDA) for the prevention and treatment of osteoporosis in postmenopausal women, as well as for the reduction of the risk of invasive breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer.

Active ingredient of raloxifene

The active ingredient of raloxifene is raloxifene hydrochloride.

US brand name of raloxifene and manufacturer

Raloxifene is available in the US under the brand name Evista. The manufacturer is Eli Lilly and Company.

UK brand name of raloxifene and manufacturer

In the UK, raloxifene is available under the brand name Evista. The manufacturer is also Eli Lilly and Company.

Prescription requirement for raloxifene

A prescription (Rx) is required for raloxifene in both the US and the UK.

Availability of raloxifene in the UK with NHS prescription

Raloxifene is available in the UK with an NHS prescription.

Conditions treated by raloxifene

Raloxifene is primarily used for the treatment and prevention of osteoporosis in postmenopausal women (after menopause). Osteoporosis causes an increased risk for bone fractures. Raloxifene can also reduce the risk of invasive breast cancer and increase bone mineral density in postmenopausal women with osteoporosis or at high risk for breast cancer.

How does raloxifene work?

Raloxifene is a selective estrogen receptor modulator (SERM), with an estrogen-agonistic effect. It acts by binding to estrogen receptors in certain tissues, mimicking the beneficial effects of estrogen on bone density, while blocking the negative effects on the breast and uterus. This helps to prevent bone loss and reduce the risk of breast cancer.

Forms of raloxifene available

Raloxifene is available in oral tablet form.

Dosage of raloxifene

The dosage of raloxifene may vary depending on the specific condition being treated and individual patient factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for raloxifene use

Raloxifene should be taken as directed by the healthcare provider. It is usually taken once daily, with or without food. It is important to take raloxifene regularly to maximize its effectiveness.

Warnings and precautions for raloxifene

  • Raloxifene may increase the risk of blood clots, stroke, and other serious cardiovascular events. It should not be used in individuals with a history of blood clots or stroke
  • It is important to inform the healthcare provider about any existing medical conditions, allergies, and any other medications or supplements you are currently taking, to avoid potential drug interactions
  • Tell your doctor if you have ever had heart problems, such as heart disease, heart attack or stroke, high blood pressure, blood clots, high triglycerides or cholesterol caused by estrogen, kidney disease, or abnormal vaginal bleeding
  • Monitor for thromboembolic events such as deep vein thrombosis (DVT). Symptoms include red, tender and inflamed calves and lower limbs
  • It is not known if raloxifene passes into breast milk. Speak to your doctor before breast-feeding
  • Make sure you get plenty of calcium and vitamin D in your diet when taking raloxifene

Possible side effects of raloxifene

In clinical trials common side effects of raloxifene may include hot flashes, leg cramps, and swelling of the legs. Serious side effects, such as blood clots or stroke, are rare but can occur. If any unusual or severe adverse effects (such as sudden chest pain, shortness of breath, loss of vision or blurred vision) are experienced, it is important to contact a healthcare provider.

Interactions with other drugs

Raloxifene may interact with other medications, including anticoagulants such as warfarin, cholestyramine, and medications containing estrogen such as hormone replacement therapy. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medication, supplements, and vitamins you are taking to avoid potential drug interactions.

Similar drugs to raloxifene

Other medications, such as bisphosphonates (e.g., alendronate) and selective estrogen receptor modulators (e.g., tamoxifen), may be used as alternatives to raloxifene for the prevention and treatment of osteoporosis.


Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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