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Prolia is the brand name for denosumab subcutaneous injection.

Prolia is available as a single-dose prefilled syringe containing 60 mg in a 1 mL
solution.

Prolia is a monoclonal antibody and is used for the following:
Osteoporosis in females who’ve gone through menopause
Osteoporosis in males
Osteoporosis caused by certain steroid medications
Bone loss in males taking certain medications for prostate cancer
Bone loss in females taking certain breast cancer medications

Prolia is a monoclonal antibody. It blocks a protein in your body that sends signals to break down your bones. This prevents bone loss and helps strengthen your bones.

Prolia is an injection that’s typically given to you by your healthcare provider.

The typical recommended dose is 60 mg injected under the skin of your upper arm, upper thigh, or stomach once every 6 months.

Prolia is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
Hypocalcemia.
Pregnancy.
Known hypersensitivity to Prolia.

Common side effects of Prolia:

• Back pain
• Pain in your arms and legs
• Pain in your muscles, bones, joints, or nerves
• High cholesterol levels
• Pain or discomfort while urinating and other symptoms of a bladder infection
• Sensation that the room is spinning
• Swelling in the hands and feet
• Cough, sore throat, and other symptoms of an upper respiratory tract infection

Serious side effects are rare with Prolia. Serious Side Effects
Contact your healthcare provider immediately if you experience any of the following.

Serious allergic reactions: dizziness, trouble, tightness in your throat, swelling in your face and throat, itchiness, rash

There are no major drug interactions listed for Prolia. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Amgen Inc.

Prolia may harm your unborn baby.
Females who are able to become pregnant:
Your healthcare provider should do a pregnancy test before you start treatment with Prolia.
You should use an effective method of birth control (contraception) during treatment with Prolia and for at least 5 months after your last dose of Prolia.
Tell your doctor right away if you become pregnant while taking Prolia.

• Denosumab