PRILOSEC OTC
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Manufactured by AstraZeneca
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PRILOSEC OTC Uses, Side Effects, Interactions, Warnings & Dosing
What is PRILOSEC OTC?
PRILOSEC OTC is the brand name for omeprazole and is available as an oral tablet.
What dosages is PRILOSEC OTC available in?
PRILOSEC OTC is available as a 20 mg oral tablet.
What is PRILOSEC OTC used for?
PRILOSEC OTC is a proton pump inhibitor that is used to treat heartburn.
How does PRILOSEC OTC work?
PRILOSEC OTC is a proton pump inhibitor (PPI). It blocks acid from getting “pumped” into the stomach. This helps relieve heartburn and other medical conditions that cause too much stomach acid.
How do I take PRILOSEC OTC?
PRILOSEC OTC is typically taken as 20 mg by mouth once daily in the morning for 2 weeks.
Is it safe for me to take PRILOSEC OTC?
PRILOSEC OTC is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to any component of the formulation or substituted benzimidazoles (angioedema and anaphylaxis have occurred)
PRILOSEC OTC Common Side Effects
Common side effects of PRILOSEC OTC:
- Headache
- Belly pain
- Nausea
- Diarrhea
- Vomiting
- Passing gas
PRILOSEC OTC Serious Side Effects
Serious side effects are rare with PRILOSEC OTC. Contact your healthcare provider immediately if you experience any of the following.
- Severe stomach pain or diarrhea
- Kidney problems: urinating more or less than usual, fever, poor appetite, blood in urine
- Lupus symptoms: joint pain, skin rash on arms or cheeks that gets worse in the sunlight
- Serious allergic reaction: blistering, peeling, or bleeding skin; fever; chills; trouble breathing; face swelling
Effects of other drugs, drug classes and over-the-counter products on PRILOSEC OTC
The following medications may interact with PRILOSEC OTC:
- Atazanavir and nelfinavir: PRILOSEC OTC reduces plasma levels of atazanavir and nelfinavir. Concomitant use is not recommended
- Saquinavir: PRILOSEC OTC increases plasma levels of saquinavir. Monitor for toxicity and consider dose reduction of saquinavir
- May interfere with drugs for which gastric pH affects bioavailability (e.g., ketoconazole, iron salts, ampicillin esters, and digoxin)
- Patients treated with PRILOSEC OTC and digoxin may need to be monitored for increases in digoxin toxicity.
- Co-administration of clopidogrel with 80 mg omeprazole may reduce the pharmacological activity of clopidogrel if given concomitantly or if given 12 hours apart.
- Cilostazol: PRILOSEC OTC increases systemic exposure of cilostazol and one of its active metabolites. Consider dose reduction of cilostazol
- Drugs metabolized by cytochrome P450 (e.g., diazepam, warfarin, phenytoin, cyclosporine, disulfiram, benzodiazepines): PRILOSEC can prolong their elimination. Monitor and determine need for dose adjustments
- Patients treated with proton pump inhibitors and warfarin may need to be monitored for increases in INR and prothrombin time
- Combined inhibitor of CYP 2C19 and 3A4 (e.g. voriconazole) may raise omeprazole levels
- Tacrolimus: PRILOSEC OTC may increase serum levels of tacrolimus
- Methotrexate: PRILOSEC OTC may increase serum levels of methotrexate
Who makes PRILOSEC OTC?
AstraZeneca
Is PRILOSEC OTC safe in pregnancy?
It is not known if PRILOSEC OTC will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
What to do if you missed your PRILOSEC OTC dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
Is it OK to take Prilosec OTC every day?
Can you stay on omeprazole for life?
What is the safest PPI for long term use?
Is Prilosec better than omeprazole?
What is the best long term medication for GERD?
Does Prilosec cause weight gain?
When is the best time of day to take Prilosec?
How I cured my acid reflux?
What is the difference between Prilosec and Prilosec OTC?
What is the safest PPI to take long term?
Why is Prilosec 14 days?
How long does it take for Prilosec to start working?
What is a natural alternative to Prilosec OTC?
What should I take instead of Prilosec?
Which is better Pepcid or Prilosec?
What is the safest drug for acid reflux?
Why can't you take Prilosec for more than 14 days?
Which works better Zantac or Prilosec?
Can I take Prilosec and Pepcid at the same time?
Can I take Tums and Prilosec together?
Can I take Prilosec in the morning and Pepcid at night?
Is it bad to take Pepcid every day?
Which is safer long term omeprazole or famotidine?
Which antacid is safe for long term use?
When is the best time to take Prilosec?
Is Pepcid or Tums better for acid reflux?
Is it better to take Pepcid in the morning or at night?
What are the side effects of Prilosec OTC?
What to avoid when taking Prilosec?
What is the biggest side effect of omeprazole?
Is Prilosec bad for your gut?
What is the lawsuit against Prilosec?
Should Prilosec OTC be taken in the morning or night?
Who should avoid omeprazole?
Is it bad to take omeprazole every day?
What foods neutralize stomach acid immediately?
What is the best time of day to take Prilosec?
What can I take instead of omeprazole?
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