Used for Depression

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Manufactured by various FDA-approved generic manufacturers.

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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

paroxetine Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is paroxetine available in?

What dosages is paroxetine available in?

paroxetine is available as a 10 mg, 20 mg, 30 mg, and 40 mg oral tablet and a 10 mg/5 ml oral suspension.

What is paroxetine used for?

What is paroxetine used for?

paroxetine is an SSRI and is used to treat:

  • Depression
  • Panic disorder (PD)
  • Social anxiety disorder (SAD)
  • Obsessive-compulsive disorder (OCD)
  • Generalized anxiety disorder (GAD)
  • Post-traumatic stress disorder (PTSD)
How does paroxetine work?

How does paroxetine work?

paroxetine is a selective serotonin reuptake inhibitor (SSRI). It works by raising the levels of serotonin, an important chemical in your brain that’s involved with regulating your mood.

How do I take paroxetine?

How do I take paroxetine?

paroxetine is typically given in dose ranges from 10 mg to 60 mg by mouth once per day.

Is it safe for me to take paroxetine?

Is it safe for me to take paroxetine?

paroxetine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are currently taking pimozide or thioridazine or have taken an MAOI within the past 14 days.

paroxetine Common Side Effects

paroxetine Common Side Effects

Common side effects of paroxetine:

  • Abnormal ejaculation
  • Nausea
  • Weakness
  • Sleepiness or trouble sleeping
  • Dry mouth
  • Constipation
  • Sweating
  • Dizziness
  • Diarrhea
  • Low libido
  • Shakiness
paroxetine Serious Side Effects

paroxetine Serious Side Effects

Serious side effects are rare with paroxetine. Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
  • Seizures
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
  • Severe bleeding: bruising that doesn’t improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
  • Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
Effects of other drugs, drug classes and over-the-counter products on paroxetine

Effects of other drugs, drug classes and over-the-counter products on paroxetine

The following medications may interact with paroxetine:

  • Drugs Highly Bound to Plasma Protein: Monitor for adverse reactions and reduce dosage of paroxetine or other protein-bound drugs (e.g., warfarin) as warranted
  • Drugs Metabolized by CYP2D6: Reduce dosage of drugs metabolized by CYP2D6 as warranted
  • Concomitant use with Tamoxifen: Consider use of an alternative antidepressant with little or no CYP2D6 inhibition
Who makes paroxetine?

Who makes paroxetine?

Various FDA-approved generic manufacturers

Is paroxetine safe in pregnancy?

Is paroxetine safe in pregnancy?

paroxetine can cause fetal harm when administered to a pregnant woman. If paroxetine is used during pregnancy, or if you become pregnant while taking paroxetine, you should talk to your provider about the risks.


What to do if you missed your paroxetine dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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