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Onabotulinumtoxina is available as 100 Units or 200 Units for injection, for intramuscular, intradetrusor, or intradermal use.

• Onabotulinumtoxina is a neuromuscular blocker and is used to temporarily improve the appearance of frown lines, forehead lines, and crow’s feet lines in adults

Onabotulinumtoxina is a neuromuscular blocker. It’s a toxin made from bacteria (Clostridium botulinum) that temporarily lowers muscle activity by stopping a chemical called acetylcholine from being released in your muscle. This helps to relax the muscles that cause frown lines, forehead lines, and crow’s feet lines around your eyes.

• The dose of Onabotulinumtoxina can differ depending on which area of the face is being treated. Typically, you can receive an injection into a particular area at most once every 3 months. The maximum total dose is 400 units in a 3-month period

Onabotulinumtoxina is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an infection at the injection site.

Common side effects of Onabotulinumtoxina:

• Drooping eyelids
• Facial pain
• Trouble moving parts of the face
• Muscle weakness
• Crow’s feet
• Eyelid swelling
• Forehead lines
• Headache
• Drooping eyebrow
• Skin tightness

Serious side effects are rare with Onabotulinumtoxina. Contact your healthcare provider immediately if you experience any of the following.

• Trouble breathing or swallowing

The following medications may interact with Onabotulinumtoxina:

• Patients receiving concomitant treatment of Onabotulinumtoxina and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., curare-like agents), or muscle relaxants, should be observed closely because the effect of Onabotulinumtoxina may be potentiated

Various FDA-approved generic manufacturers

Onabotulinumtoxina Based on animal data, may cause fetal harm. You should talk to your healthcare provider before taking this medication if you are pregnant.

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