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Novolin R is the brand name for insulin human and is available as an injection for subcutaneous or IV use.

Novolin R is available as a vial and FlexPen that contains 100 units/ml.

Novolin R is an insulin and is used for the following:

• Type 1 diabetes
• Type 2 diabetes

Novolin R is a short-acting insulin. Insulin is a natural hormone your body normally makes to lower glucose (sugar) levels in the blood. It helps your body absorb and store sugar and fat from your bloodstream after eating a meal.

The dose of Novolin R will be different for each person. The dose depends on whether you’re using it for type 1 diabetes or type 2 diabetes, your weight, how well you respond to insulin, and your blood sugar levels. Please follow the directions from your provider carefully.

• Novolin R is typically injected underneath the skin (subcutaneously) before each meal

Novolin R is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of hypoglycemia.

Common side effects of Novolin R:

• Low blood sugar (hypoglycemia)
• Injection site reactions (e.g., redness, warmth, changes in skin color)
• Buildup or loss of fat tissue (lipodystrophy)
• Weight gain
• Swelling (edema)

Serious side effects are rare with Novolin R. Contact your healthcare provider immediately if you experience any of the following.

• Severe hypoglycemia (dangerously low blood sugar): if not treated, severe hypoglycemia can lead to unconsciousness, seizures, and even death
• Severe allergic reactions: rash, hives, swelling of face, tongue, and throat, difficulty breathing
  Dangerously low levels of potassium: if not treated, it can lead to difficulty breathing, irregular heartbeat, and even death

The following medications may interact with Novolin R:

• Drugs that may increase the risk of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g. octreotide), and sulfonamide antibiotics
• Drugs that may decrease the blood glucose lowering effect:atypical antipsychotics, corticosteroids, danazol, diuretics estrogens, glucagon, isoniazid, niacin, oral contraceptives phenothiazines, progestogens (e.g., in oral contraceptives) protease inhibitors, somatropin, sympathomimetic agents (e.g. albuterol, epinephrine, terbutaline), and thyroid hormones
• Drugs that may increase or decrease the blood glucose lowering effect: alcohol, beta-blockers, clonidine, lithium salts, and pentamidine
• Drugs that may blunt the signs and symptoms of hypoglycemia: beta-blockers, clonidine, guanethidine, and reserpine

Novo Nordisk Inc.

Published studies with Novolin R used during pregnancy have not reported an association between its use and the induction of major birth defects, miscarriage, or adverse maternal or fetal outcomes. If you become pregnant while receiving Novolin R, talk to your healthcare provider.

• Regular, Human Insulin [rdna Origin] Injection