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Nirsevimab-Alip is available as a 50 mg/0.5 mL in a single-dose pre-filled syringe or 100 mg/mL in a single-dose pre-filled syringe.

Nirsevimab-Alip is a monoclonal antibody that is used for the prevention of respiratory syncytial virus (RSV) in:
Newborns and infants during or entering their first RSV season
Children up to 24 months old at risk for severe RSV illness through their second RSV season

Nirsevimab-Alip is an injection of monoclonal antibodies (manmade proteins) which provides protection against the respiratory syncytial virus (RSV). The antibodies attach to the virus and stop it from entering cells and spreading.

Nirsevimab-Alip is injected into the muscle by a trained healthcare provider.

Newborns and infants born during or entering their first RSV season:

• Weight less than 5 kg (11 lbs): The typical dose is 50 mg given as one dose
• Weight 5 kg (11 lbs) and more: The typical dose is 100 mg given as one dose

Children up to 24 months old at risk for severe RSV illness in their second RSV season:

• The typical dose is 200 mg given as two 100 mg injections in one office visit

Nirsevimab-Alip is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. Nirsevimab-Alip is contraindicated in infants and children with a history of serious
hypersensitivity reactions, including anaphylaxis, to Nirsevimab-Alip or to any of the excipients.

Common side effects of Nirsevimab-Alip:

• Rash
• Injection site reaction (e.g., pain, hard lump, swelling)

Serious side effects are rare with Nirsevimab-Alip. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reaction: rash, trouble breathing, swelling in the face or throat

• There are no major drug interactions listed for Nirsevimab-Alip. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Various FDA-approved generic manufacturers

Nirsevimab-Alip is not indicated for use in females of reproductive potential.

• Beyfortus