Key facts about Mosunetuzumab-AXGB
What dosages is Mosunetuzumab-AXGB available in?
Mosunetuzumab-AXGB is available as a 1 mg/mL and 30 mg/30 mL (1 mg/mL) single-dose vial.
What is Mosunetuzumab-AXGB used for?
Mosunetuzumab-AXGB is a bispecific CD20-directed CD3 T-cell engager used for the the treatment of adult patients with relapsed or refractory lymphoma after two or more lines of systemic therapy.
How does Mosunetuzumab-AXGB work?
Mosunetuzumab-AXGB works by helping your immune system slow or stop the spread of cancer cells.
How do I take Mosunetuzumab-AXGB?
Mosunetuzumab-AXGB is injected into a vein. It is given by your care team in a hospital or clinic setting.
Is it safe for me to take Mosunetuzumab-AXGB?
Mosunetuzumab-AXGB is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Mosunetuzumab-AXGB Common Side Effects
Common side effects of Mosunetuzumab-AXGB:
- Back pain
- Cough
- Fatigue
- Headache
- Muscle pain
Mosunetuzumab-AXGB Serious Side Effects
Serious side effects are rare with Mosunetuzumab-AXGB. Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Infection—fever, chills, cough, sore throat, wounds that don’t heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Pain, tingling, or numbness in the hands or feet, muscle weakness, headache, change in vision, confusion or trouble speaking, dizziness, loss of balance or coordination, trouble walking, tremors or shaking, seizures
- Swelling and pain of the tumor site or lymph nodes
- Unusual bruising or bleeding
Effects of other drugs, drug classes and over-the-counter products on Mosunetuzumab-AXGB
The following medications may interact with Mosunetuzumab-AXGB:
- Monitor for toxicity or concentrations of drugs that are CYP450 substrates where minimal concentration changes may lead to serious adverse reactions. Consult the concomitant CYP450 substrate drug prescribing information for recommended dosage modification
Who makes Mosunetuzumab-AXGB?
Various FDA-approved generic manufacturers
Is Mosunetuzumab-AXGB safe in pregnancy?
Mosunetuzumab-AXGB may harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with Mosunetuzumab-AXGB. Females who are able to become pregnant: Your healthcare provider should do a pregnancy test before you start treatment with Mosunetuzumab-AXGB.
You should use an effective method of birth control during your treatment and for 3 months after the last dose of Mosunetuzumab-AXGB.
