Key facts about Midodrine
What dosages is Midodrine available in?
Midodrine is available as a 2.5 mg, 5 mg, and 10 mg oral tablet.
What is Midodrine used for?
Midodrine is a alpha-1 adrenergic receptor agonist that is used to treat orthostatic hypotension.
How does Midodrine work?
Midodrine is an alpha-1 adrenergic receptor agonist. It raises blood pressure by tightening the blood vessels in the body.
How do I take Midodrine?
Midodrine is typically taken as 10 mg by mouth 3 times daily. Your dose might differ if you have kidney problems.
Is it safe for me to take Midodrine?
Midodrine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have severe organic heart disease, acute renal disease, urinary retention, pheochromocytoma or thyrotoxicosis.
Midodrine Common Side Effects
Common side effects of Midodrine:
- Tingling or pricking feeling
- Goosebumps
- Painful urination
- Itchy skin
- High blood pressure when lying down
- Chills
- Pain
- Rash
Midodrine Serious Side Effects
Serious side effects are rare with Midodrine. Contact your healthcare provider immediately if you experience any of the following.
- High blood pressure (more than 200 mmHg) when lying down: changes in heartbeat, pounding in the ears, headache, blurred vision
Effects of other drugs, drug classes and over-the-counter products on Midodrine
The following medications may interact with Midodrine:
- When administered concomitantly with Midodrine , cardiac glycosides may enhance or precipitate bradycardia, A.V. block or arrhythmia
- The risk of hypertension increases with concomitant administration of drugs that increase blood pressure (phenylephrine, pseudoephedrine, ephedrine, dihydroergotamine, thyroid hormones, or droxidopa). Avoid concomitant use of drugs that increase blood pressure. If concomitant use cannot be avoided, monitor blood pressure closely
- Avoid use of MAO inhibitors or linezolid with Midodrine
- Midodrine has been used in patients concomitantly treated with salt-retaining steroid therapy (i.e., fludrocortisone acetate), with or without salt supplementation. The potential for supine hypertension should be carefully monitored in these patients
Who makes Midodrine?
Various FDA-approved generic manufacturers
Is Midodrine safe in pregnancy?
It is not known if Midodrine will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
