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Lovenox is the brand name for enoxaparin sodium injection for subcutaneous and intravenous use.

Lovenox is available in strengths of 100 mg/mL and 150 mg/mL injections.

Lovenox is a blood thinner used for the prevention of blood clots in the arms or legs (deep vein thrombosis or DVT) or in the lungs (pulmonary embolism or PE) in:

• People having stomach, hip, or knee surgery
• People who aren’t able to move well
• People with a certain type of chest pain called unstable angina
• Treatment of blood clots
• Heart attack

Lovenox is an anticoagulant (or blood thinner). It blocks certain proteins in your blood that are responsible for forming blood clots. This helps prevent blood clots from getting bigger and new blood clots from forming.

The dose and length of treatment depends on your age, weight, kidney function, and why you need Lovenox. The dose might also depend on certain lab test results, including complete blood count (CBC) and those measuring how long it takes for your blood to clot. In general, Lovenox is typically given as an injection under the skin (subcutaneous or SC).

Lovenox is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following.

• Active major bleeding
• Thrombocytopenia with a positive in vitro test for anti-platelet antibody in the presence of enoxaparin sodium.
  Hypersensitivity to enoxaparin sodium.
• Hypersensitivity to heparin or pork products
• Hypersensitivity to benzyl alcohol [for multi-dose formulation only

Common side effects of Lovenox:

• Abnormal liver tests
• Major bleeding
• Bleeding, bruising, redness, or pain at injection site

Serious side effects are rare with Lovenox. Contact your healthcare provider immediately if you experience any of the following.

• Severe bleeding: feeling faint, lightheadedness, dizziness, vomiting blood, bloody or dark-colored stools, severe stomach pain or discomfort
• Heparin-induced thrombocytopenia (HIT) or heparin-induced thrombocytopenia with thrombosis (HITT): skin changes or bruising, shortness of breath, chest pain or tightness, trouble speaking, numbness on one side of your body, vision problems
• Serious allergic reaction: rash; trouble breathing; swelling of the lips, tongue, or face; vomiting; chills; fever
• Blood clots due to stopping enoxaparin (Lovenox) too soon: in leg or arm (e.g., swelling or redness in arms or legs, skin that’s warm to touch); in lungs (e.g., trouble breathing, chest pain, cough, irregular heartbeat)

The following medications may interact with Lovenox:

• Discontinue agents which may enhance hemorrhage risk prior to initiation of Lovenox or conduct close clinical and laboratory monitoring

sanofi-aventis U.S.

Pregnant women with mechanical prosthetic heart valves and their fetuses, may be at increased risk of complications and may need more frequent monitoringnand dosage adjustment of Lovenox.

• Enoxaprin Sodium