LoperamidePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Loperamide HCl
    Generic for Imodium A-D
    30 capsules $6.9 USD
    Save $20.10
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Do you need a prescription for loperamide?

Yes, loperamide is only available with a valid physician Rx.

How much is loperamide without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase loperamide, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for loperamide in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a loperamide savings card?

Yes. Save up to 90% on your loperamide with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a loperamide coupon provider in the US?

No. Now Patient does not provide loperamide coupons or FREE loperamide samples.

Do you accept commercial, Medicare or Medicaid coverage for loperamide in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much loperamide?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using loperamide. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much loperamide. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

FDA approval of loperamide

Loperamide has been approved by the U.S. Food and Drug Administration (FDA) for the control and symptomatic relief of acute nonspecific diarrhea and chronic diarrhea associated with inflammatory bowel disease.

US brand name of loperamide

Loperamide is available under various brand names, including Imodium, Anti-Diarrheal, and Diamode. These brands are manufactured by different pharmaceutical companies.

UK brand name of loperamide

In the UK, loperamide is available under the brand name Imodium. This brand is manufactured by a specific pharmaceutical company.

Conditions treated by loperamide

Loperamide hydrochloride is used for the treatment of acute diarrhea, including traveler’s diarrhea. Loperamide slows gastrointestinal motility, reducing bowel movements and making the stools less watery. Loperamide also reduces the amount of discharge in those who have an ileostomy, and on-going diarrhoea in patients with inflammatory bowel disease.

Availability of loperamide

Loperamide is available over-the-counter (OTC) without a prescription. It is available as an oral capsule, liquid, suspension, tablet, or chewable tablet. Store loperamide at room temperature away from light and moisture. Keep away from children and pets.

NHS prescription (UK) for loperamide

Loperamide is available for purchase directly from pharmacies or retail stores without an NHS prescription in the UK.

Mechanism of action

Loperamide acts on mu-opioid receptors in the gut. Loperamide works by slowing down the movement of the intestines, which helps to reduce the frequency and urgency of bowel movements.

Warnings and precautions for loperamide

  • Do not use loperamide if you have ulcerative colitis, liver disease, a heart rhythm disorder, a slow or irregular heartbeat, low blood potassium levels, or diarrhea with a high fever
  • Speak to your doctor if you are taking other medications as some drug interactions may cause serious heart problems
  • Loperamide is not recommended for use in children younger than 2 years of age

Is it safe with breastfeeding?

Loperamide passes into breast milk but is not likely to cause adverse reactions on a nursing infant. Speak to a healthcare professional before breast-feeding.

Is it safe to take if I am pregnant or planning on becoming pregnant?

If you are pregnant, planning to become pregnant, or suspect you may be pregnant, it is important to discuss the use of loperamide with your healthcare provider. They can evaluate the potential risks and benefits to determine the best course of action for your specific situation.

Interactions with other drugs

Loperamide may interact with certain medications, including certain antibiotics, antifungal drugs such as itraconazole, antiretroviral drugs such as ritonavir, gemfibrozil and quinidine. It is important to inform your healthcare provider about all the medications you are taking, including over-the-counter medication, vitamins, and herbal supplements, to avoid potential interactions.

Side effects of loperamide

Common side effects of loperamide may include:

  • Constipation
  • Nausea
  • Abdominal pain, bloating
  • Dizziness, drowsiness, tiredness
  • Dry mouth

Serious adverse effects are rare but get emergency help if you have signs of an allergic reaction.

Dosage of loperamide

Take loperamide by mouth, after each loose stool. The recommended dose of loperamide may vary depending on the individual and the severity of diarrhea. Diarrhea can cause you to lose fluids and electrolytes, so make sure you drink plenty of liquids to prevent getting dehydrated. It is important to follow the instructions provided on the product label or as directed by your healthcare provider.

If you miss a dose of your medication, take it as soon as you can. If it is almost time for you next dose, skip the missed dose and take your next dose at the regular time.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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