LinezolidPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Linezolid
    Generic for Zyvox
    30 tablets $32.4 USD
    Save $1579.80
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Do you need a prescription for linezolid?

Yes, linezolid is only available with a valid physician Rx.

How much is linezolid without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase linezolid, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for linezolid in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a linezolid savings card?

Yes. Save up to 90% on your linezolid with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a linezolid coupon provider in the US?

No. Now Patient does not provide linezolid coupons or FREE linezolid samples.

Do you accept commercial, Medicare or Medicaid coverage for linezolid in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much linezolid?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using linezolid. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much linezolid. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic linezolid?

Generic linezolid refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of linezolid

Linezolid is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various bacterial infections.

Active ingredient of linezolid

The active ingredient of linezolid is linezolid.

US brand name of linezolid and manufacturer

Linezolid is available in the US under the brand name Zyvox. It is manufactured by Pfizer Inc.

UK brand name of linezolid and manufacturer

In the UK, linezolid is available under the brand name Zyvox. The manufacturer may vary depending on the brand name.

Prescription requirement for linezolid

A prescription (Rx) is required for linezolid in both the US and the UK.

Availability of linezolid in the UK with NHS prescription

Linezolid is available in the UK with an NHS prescription.

Conditions treated by linezolid

Clinical use of linezolid is primarily for the treatment of life-threatening bacterial infections caused by Gram-positive bacteria resistant to other antibiotics. Linezolid is active against vancomycin-resistant enterococci, nosocomial pneumonia, Enterococcus faecalis, Enterococcus faeciumStreptococcus, and methicillin-resistant Staphylococcus aureus (MRSA). It is bacteriocidal against most streptococci and bacteriostatic against enterococci and staphylococci. Linezolid therapy is not approved for gram-negative bacteria or catheter-related infections.

How does linezolid Work?

Linezolid belongs to a class of antibacterial medications called synthetic oxazolidinone antimicrobials (oxazolidinone antibiotic). It is also a reversible, non-selective monoamine oxidase (MAOi) inhibitor. It’s mechanism of action is to inhibit the growth of bacteria and prevent the production of proteins necessary for bacterial survival.

Forms of linezolid available

Linezolid is available in the form of oral tablets, oral suspension, and an intravenous (IV) formulation for injection. Due to its rapid and complete absorption when taken orally, linezolid has an oral bioavailability of 100%.

Dosage of linezolid

The dosage of linezolid may vary depending on the specific infection being treated, the severity of the infection, and individual patient factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for linezolid use

Linezolid should be taken exactly as directed by the healthcare provider. The medication can be taken with or without food, but it is important to maintain consistent food intake throughout the treatment period. If linezolid is administered intravenously, it should be done under the supervision of a healthcare professional.

Warnings and precautions for linezolid

  • Linezolid should be used with caution in individuals with certain medical conditions, such as liver or kidney disease. Dose adjustments may be necessary
  • Drug interactions with certain medications, including pseudoephedrine and phenylephrine. Inform the healthcare provider about all medications, vitamins and supplements being taken
  • Increased risk of serotonin syndrome/toxicity if you are taking serotonergic drugs, such as St. John’s wort, SSRIs such as paroxetine, and SNRIs such as duloxetine
  • You are advised to avoid consuming large amounts of foods and drinks containing tyramine while taking linezolid, as it will increase the effects of tyramine
  • Cases of myelosuppression (anemia, leukopenia, and thrombocytopenia) have been reported by the FDA
  • Heart rate, blood glucose, blood pressure, and a weekly complete blood count need to measured while taking linezolid

Use of linezolid during pregnancy

The use of linezolid during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of linezolid while breastfeeding

It is unknown whether linezolid passes into breast milk. It is recommended to consult a healthcare provider before using linezolid while breastfeeding.

Possible side effects of linezolid

In clinical trials, common side effects of linezolid may include diarrhea, headache, nausea, and vomiting. Serious adverse effects are rare but can include allergic reactions, extremely high blood pressure, blood disorders such as lactic acidosis, and changes in vision such as optic neuropathy. Promptly report any concerning adverse events to a healthcare provider.

Similar drugs to linezolid

Other antibiotics with similar mechanisms of action or used for similar indications include vancomycin, daptomycin, and tedizolid.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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