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Levofloxacin is available as a 250 mg, 500 mg, and 750 mg oral tablet and a 25 mg/ml oral solution.

Levofloxacin is a fluoroquinolone (or “quinolone”) antibiotic that is used to treat skin infections, sinus infections, lower respiratory tract infections (e.g., pneumonia), urinary tract infections (UTIs), kidney infections, long-term prostate infections, anthrax exposure through inhalation, and plague.

Levofloxacin is a fluoroquinolone (or “quinolone”) antibiotic. It works by blocking certain enzymes (proteins) that bacteria use to grow and repair their genetic material (DNA) in order to survive. By blocking this process, the antibiotic kills bacteria.

Levofloxacin dosing depends on your age, weight (for children), the type of infection you have, and how serious the infection is. Your dose might differ if you have kidney problems. Adults will typically take it by mouth once daily while children may take it once or twice daily.

Levofloxacin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to Levofloxacin or other quinolones.

Common side effects of Levofloxacin:

• Nausea
• Headache
• Diarrhea
• Trouble sleeping
• Dizziness
• Stomach pain
• Upset stomach

Serious side effects are rare with Levofloxacin. Contact your healthcare provider immediately if you experience any of the following.

• Achilles pain, pain or swelling at joint or muscle
  Seizures
• Changes in thoughts or behavior
• Major blood vessel damage: sudden and severe chest, back, or stomach pain; shortness of breath, pain in arms or legs; weakness
• Abnormal heart rhythm: chest pounding, chest pain, shortness of breath, feeling faint or lightheaded
• Infectious (C. difficile-related) diarrhea: foul-smelling diarrhea, frequent bowel movements, fever
• Kidney problems: urinating less often than usual, swelling, unexplained weight gain
• Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark urine
• Serious allergic and skin reactions: hives, rash, blisters, skin reddening, swelling of the lips or tongue, difficulty breathing

The following medications may interact with Levofloxacin:

• Multivalent cationcontaining products including antacids, metal cations or didanosine: Absorption of Levofloxacin is decreased when the tablet or oral solution formulation is taken within 2 hours of these products
• Warfarin: Effect may be enhanced. Monitor prothrombin time, INR, watch for bleeding
• Antidiabetic agents: Carefully monitor blood glucose

Various FDA-approved generic manufacturers

There are no adequate and well-controlled studies in pregnant women. Levofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Levaquin